Qualification of a precision pattern dispenser
In order to automate sample preparation processes, a precision pattern dispenser was designed to reproducibly dispense radioactive solutions at pre-defined positions. It is composed of an automatic liquid sample handling unit coupled to an XYZ table. Qualification tests were conducted to evaluate th...
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Veröffentlicht in: | Applied radiation and isotopes 2018-04, Vol.134, p.117-121 |
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container_title | Applied radiation and isotopes |
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creator | Van Ammel, Raf Sobiech-Matura, Katarzyna Wätjen, Uwe Vercammen, Tom Castelein, Pieter Wuyts, Roel Paul, Johan |
description | In order to automate sample preparation processes, a precision pattern dispenser was designed to reproducibly dispense radioactive solutions at pre-defined positions. It is composed of an automatic liquid sample handling unit coupled to an XYZ table. Qualification tests were conducted to evaluate the performance of the instrument and to assess the compliance with the requirements, in particular trueness (< 2%) and repeatability (< 1%). The instrument allows preparing sources in different source holders and on air filters, in a fast and accurate way.
•A precision dispenser was developed in order to automate source preparation.•Flexible to dispense pre-set amounts of liquid in different kinds of sample holders.•Different spiking patterns (size, amount per spot) can be dispensed on air filters.•Qualification proved repeatability |
doi_str_mv | 10.1016/j.apradiso.2017.06.019 |
format | Article |
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•A precision dispenser was developed in order to automate source preparation.•Flexible to dispense pre-set amounts of liquid in different kinds of sample holders.•Different spiking patterns (size, amount per spot) can be dispensed on air filters.•Qualification proved repeatability <1 %, trueness <2% in range of 20μL to 4mL.•A series of 1100 sources was produced with excellent repeatability and trueness.</description><identifier>ISSN: 0969-8043</identifier><identifier>EISSN: 1872-9800</identifier><identifier>DOI: 10.1016/j.apradiso.2017.06.019</identifier><identifier>PMID: 28648473</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Automatic dispensing ; Qualification ; Source preparation ; Spiking</subject><ispartof>Applied radiation and isotopes, 2018-04, Vol.134, p.117-121</ispartof><rights>2017 The Authors</rights><rights>Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c464t-be772346ebb3ba043de07028824fe001df0c533b395cf9c40c276268c56d46bb3</citedby><cites>FETCH-LOGICAL-c464t-be772346ebb3ba043de07028824fe001df0c533b395cf9c40c276268c56d46bb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0969804317303366$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28648473$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Van Ammel, Raf</creatorcontrib><creatorcontrib>Sobiech-Matura, Katarzyna</creatorcontrib><creatorcontrib>Wätjen, Uwe</creatorcontrib><creatorcontrib>Vercammen, Tom</creatorcontrib><creatorcontrib>Castelein, Pieter</creatorcontrib><creatorcontrib>Wuyts, Roel</creatorcontrib><creatorcontrib>Paul, Johan</creatorcontrib><title>Qualification of a precision pattern dispenser</title><title>Applied radiation and isotopes</title><addtitle>Appl Radiat Isot</addtitle><description>In order to automate sample preparation processes, a precision pattern dispenser was designed to reproducibly dispense radioactive solutions at pre-defined positions. It is composed of an automatic liquid sample handling unit coupled to an XYZ table. Qualification tests were conducted to evaluate the performance of the instrument and to assess the compliance with the requirements, in particular trueness (< 2%) and repeatability (< 1%). The instrument allows preparing sources in different source holders and on air filters, in a fast and accurate way.
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•A precision dispenser was developed in order to automate source preparation.•Flexible to dispense pre-set amounts of liquid in different kinds of sample holders.•Different spiking patterns (size, amount per spot) can be dispensed on air filters.•Qualification proved repeatability <1 %, trueness <2% in range of 20μL to 4mL.•A series of 1100 sources was produced with excellent repeatability and trueness.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>28648473</pmid><doi>10.1016/j.apradiso.2017.06.019</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Automatic dispensing Qualification Source preparation Spiking |
title | Qualification of a precision pattern dispenser |
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