Medulloblastoma: From Myth to Molecular

Current therapies for medulloblastoma were introduced primarily in the 1980s and consist of predominantly cytotoxic, nontargeted approaches. Mortality from medulloblastoma remains significant. In addition, many survivors suffer from severe treatment-related effects of radiation and cytotoxic chemoth...

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Veröffentlicht in:	Journal of clinical oncology 2017-07, Vol.35 (21), p.2355-2363
Hauptverfasser:	Ramaswamy, Vijay, Taylor, Michael D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - analysis Cerebellar Neoplasms - classification Cerebellar Neoplasms - pathology Cerebellar Neoplasms - therapy Child Child, Preschool Hedgehog Proteins - analysis Humans Infant Medulloblastoma - classification Medulloblastoma - pathology Medulloblastoma - therapy Neoplasm Recurrence, Local - pathology Neoplasm Recurrence, Local - therapy Prognosis Quality of Life Risk Assessment Wnt Proteins - analysis
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