Autophagy and hypoxic ischemic brain injuries
Autophagy is a highly evolutionarily conserved physiological mechanism of organism, including several stages such as autophagosomes formation, the fusion of lysosomes and autophagosomes, and autophagosomes degradation. In physiological conditions, autophagy is responsible for clearing the spoiled or...
Gespeichert in:
| Veröffentlicht in: | Sheng li hsüeh pao 2017-06, Vol.69 (3), p.316-324 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | chi |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 324 |
|---|---|
| container_issue | 3 |
| container_start_page | 316 |
| container_title | Sheng li hsüeh pao |
| container_volume | 69 |
| creator | Li, Yong-Qiang Fu, Su Wang, Lai Liu, Bin Shi, Zhen-Yu Deng, Jin-Bo |
| description | Autophagy is a highly evolutionarily conserved physiological mechanism of organism, including several stages such as autophagosomes formation, the fusion of lysosomes and autophagosomes, and autophagosomes degradation. In physiological conditions, autophagy is responsible for clearing the spoiled organelles and long-lived proteins to maintain the homeostasis of cells and organism. Meanwhile, autophagy is also involved in the formation and development of diseases, but the mechanism has not been confirmed yet. The relationship between autophagy and hypoxic ischemic brain injuries represented by stroke is a research hotpot in recent years, but there is no clear conclusion about autophagy's role and mechanism in hypoxic ischemic brain injuries. We reviewed the activation, function and mechanism of autophagy in hypoxic ischemic brain injuries, in order to provide some perspectives on these researches. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1912614162</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1912614162</sourcerecordid><originalsourceid>FETCH-LOGICAL-p126t-395c267194732a67d11eca2424d8d2d65ed9aff2a11de7a6a051cf5ce1a6d29a3</originalsourceid><addsrcrecordid>eNo1j0trwzAQhHVoaUKav1B87MXgXcmSdQyhLwjk0p7NWlrXKn7VsqH59zU0Pc0chplvbsQ2kwbSrDBqI_YxhirLQRqlCnMnNlhoWVjMtyI9LPMwNvR5Saj3SXMZh5_gkhBdw91qqolCn4T-a5kCx3txW1MbeX_Vnfh4fno_vqan88vb8XBKR0A9p9LmDrUBq4xE0sYDsCNUqHzh0eucvaW6RgLwbEjTyubq3DGQ9mhJ7sTjX-84Dd8Lx7nsViJuW-p5WGIJdt0BBRrX6MM1ulQd-3KcQkfTpfy_KH8BQvJMRQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1912614162</pqid></control><display><type>article</type><title>Autophagy and hypoxic ischemic brain injuries</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Li, Yong-Qiang ; Fu, Su ; Wang, Lai ; Liu, Bin ; Shi, Zhen-Yu ; Deng, Jin-Bo</creator><creatorcontrib>Li, Yong-Qiang ; Fu, Su ; Wang, Lai ; Liu, Bin ; Shi, Zhen-Yu ; Deng, Jin-Bo</creatorcontrib><description>Autophagy is a highly evolutionarily conserved physiological mechanism of organism, including several stages such as autophagosomes formation, the fusion of lysosomes and autophagosomes, and autophagosomes degradation. In physiological conditions, autophagy is responsible for clearing the spoiled organelles and long-lived proteins to maintain the homeostasis of cells and organism. Meanwhile, autophagy is also involved in the formation and development of diseases, but the mechanism has not been confirmed yet. The relationship between autophagy and hypoxic ischemic brain injuries represented by stroke is a research hotpot in recent years, but there is no clear conclusion about autophagy's role and mechanism in hypoxic ischemic brain injuries. We reviewed the activation, function and mechanism of autophagy in hypoxic ischemic brain injuries, in order to provide some perspectives on these researches.</description><identifier>ISSN: 0371-0874</identifier><identifier>PMID: 28638925</identifier><language>chi</language><publisher>China</publisher><subject>Animals ; Autophagy ; Homeostasis ; Humans ; Hypoxia-Ischemia, Brain - physiopathology ; Lysosomes</subject><ispartof>Sheng li hsüeh pao, 2017-06, Vol.69 (3), p.316-324</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28638925$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Yong-Qiang</creatorcontrib><creatorcontrib>Fu, Su</creatorcontrib><creatorcontrib>Wang, Lai</creatorcontrib><creatorcontrib>Liu, Bin</creatorcontrib><creatorcontrib>Shi, Zhen-Yu</creatorcontrib><creatorcontrib>Deng, Jin-Bo</creatorcontrib><title>Autophagy and hypoxic ischemic brain injuries</title><title>Sheng li hsüeh pao</title><addtitle>Sheng Li Xue Bao</addtitle><description>Autophagy is a highly evolutionarily conserved physiological mechanism of organism, including several stages such as autophagosomes formation, the fusion of lysosomes and autophagosomes, and autophagosomes degradation. In physiological conditions, autophagy is responsible for clearing the spoiled organelles and long-lived proteins to maintain the homeostasis of cells and organism. Meanwhile, autophagy is also involved in the formation and development of diseases, but the mechanism has not been confirmed yet. The relationship between autophagy and hypoxic ischemic brain injuries represented by stroke is a research hotpot in recent years, but there is no clear conclusion about autophagy's role and mechanism in hypoxic ischemic brain injuries. We reviewed the activation, function and mechanism of autophagy in hypoxic ischemic brain injuries, in order to provide some perspectives on these researches.</description><subject>Animals</subject><subject>Autophagy</subject><subject>Homeostasis</subject><subject>Humans</subject><subject>Hypoxia-Ischemia, Brain - physiopathology</subject><subject>Lysosomes</subject><issn>0371-0874</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j0trwzAQhHVoaUKav1B87MXgXcmSdQyhLwjk0p7NWlrXKn7VsqH59zU0Pc0chplvbsQ2kwbSrDBqI_YxhirLQRqlCnMnNlhoWVjMtyI9LPMwNvR5Saj3SXMZh5_gkhBdw91qqolCn4T-a5kCx3txW1MbeX_Vnfh4fno_vqan88vb8XBKR0A9p9LmDrUBq4xE0sYDsCNUqHzh0eucvaW6RgLwbEjTyubq3DGQ9mhJ7sTjX-84Dd8Lx7nsViJuW-p5WGIJdt0BBRrX6MM1ulQd-3KcQkfTpfy_KH8BQvJMRQ</recordid><startdate>20170625</startdate><enddate>20170625</enddate><creator>Li, Yong-Qiang</creator><creator>Fu, Su</creator><creator>Wang, Lai</creator><creator>Liu, Bin</creator><creator>Shi, Zhen-Yu</creator><creator>Deng, Jin-Bo</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20170625</creationdate><title>Autophagy and hypoxic ischemic brain injuries</title><author>Li, Yong-Qiang ; Fu, Su ; Wang, Lai ; Liu, Bin ; Shi, Zhen-Yu ; Deng, Jin-Bo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-395c267194732a67d11eca2424d8d2d65ed9aff2a11de7a6a051cf5ce1a6d29a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Autophagy</topic><topic>Homeostasis</topic><topic>Humans</topic><topic>Hypoxia-Ischemia, Brain - physiopathology</topic><topic>Lysosomes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Yong-Qiang</creatorcontrib><creatorcontrib>Fu, Su</creatorcontrib><creatorcontrib>Wang, Lai</creatorcontrib><creatorcontrib>Liu, Bin</creatorcontrib><creatorcontrib>Shi, Zhen-Yu</creatorcontrib><creatorcontrib>Deng, Jin-Bo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Sheng li hsüeh pao</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Yong-Qiang</au><au>Fu, Su</au><au>Wang, Lai</au><au>Liu, Bin</au><au>Shi, Zhen-Yu</au><au>Deng, Jin-Bo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Autophagy and hypoxic ischemic brain injuries</atitle><jtitle>Sheng li hsüeh pao</jtitle><addtitle>Sheng Li Xue Bao</addtitle><date>2017-06-25</date><risdate>2017</risdate><volume>69</volume><issue>3</issue><spage>316</spage><epage>324</epage><pages>316-324</pages><issn>0371-0874</issn><abstract>Autophagy is a highly evolutionarily conserved physiological mechanism of organism, including several stages such as autophagosomes formation, the fusion of lysosomes and autophagosomes, and autophagosomes degradation. In physiological conditions, autophagy is responsible for clearing the spoiled organelles and long-lived proteins to maintain the homeostasis of cells and organism. Meanwhile, autophagy is also involved in the formation and development of diseases, but the mechanism has not been confirmed yet. The relationship between autophagy and hypoxic ischemic brain injuries represented by stroke is a research hotpot in recent years, but there is no clear conclusion about autophagy's role and mechanism in hypoxic ischemic brain injuries. We reviewed the activation, function and mechanism of autophagy in hypoxic ischemic brain injuries, in order to provide some perspectives on these researches.</abstract><cop>China</cop><pmid>28638925</pmid><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0371-0874 |
| ispartof | Sheng li hsüeh pao, 2017-06, Vol.69 (3), p.316-324 |
| issn | 0371-0874 |
| language | chi |
| recordid | cdi_proquest_miscellaneous_1912614162 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Autophagy Homeostasis Humans Hypoxia-Ischemia, Brain - physiopathology Lysosomes |
| title | Autophagy and hypoxic ischemic brain injuries |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T02%3A39%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Autophagy%20and%20hypoxic%20ischemic%20brain%20injuries&rft.jtitle=Sheng%20li%20hsu%CC%88eh%20pao&rft.au=Li,%20Yong-Qiang&rft.date=2017-06-25&rft.volume=69&rft.issue=3&rft.spage=316&rft.epage=324&rft.pages=316-324&rft.issn=0371-0874&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E1912614162%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1912614162&rft_id=info:pmid/28638925&rfr_iscdi=true |