Tissue alignment enhances remodeling potential of tendon-derived cells - Lessons from a novel microtissue model of tendon scarring

Tendinopathy is a widespread and unresolved clinical challenge, in which associated pain and hampered mobility present a major cause for work-related disability. Tendinopathy associates with a change from a healthy tissue with aligned extracellular matrix (ECM) and highly polarized cells that are co...

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Veröffentlicht in:	Matrix biology 2018-01, Vol.65, p.14-29
Hauptverfasser:	Foolen, Jasper, Wunderli, Stefania L., Loerakker, Sandra, Snedeker, Jess G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anisotropy Cell interactions Collagen Connexin 43 Exercise Extracellular matrix Gap junctions Gene expression Pain Scars Tendons
Online-Zugang:	Volltext
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