Capillary zone electrophorsis for the analysis of naturally occurring 2‐hydroxycitric acids and their lactones
A simple capillary zone electrophoresis method with direct ultraviolet detection has been developed for the analysis of naturally occurring diastereomeric 2‐hydroxycitric acid lactones. Using 50 mM sodium phosphate buffer of pH 7, a baseline resolution Rs > 3.0 was observed for all organic acids...
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| Veröffentlicht in: | Journal of separation science 2017-08, Vol.40 (16), p.3351-3357 |
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| container_issue | 16 |
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| container_title | Journal of separation science |
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| creator | Abhijith, B. L. Mohan, Moolya Joseph, David Haleema, Simimole Aboul‐Enein, Hassan Y. Ibnusaud, Ibrahim |
| description | A simple capillary zone electrophoresis method with direct ultraviolet detection has been developed for the analysis of naturally occurring diastereomeric 2‐hydroxycitric acid lactones. Using 50 mM sodium phosphate buffer of pH 7, a baseline resolution Rs > 3.0 was observed for all organic acids selected for the present study. This method was employed for the quantitative determination of title acids present in the plant sources namely Garcinia cambogia fruit rinds and Hibiscus sabdariffa calyx. Conversion of 2‐hydroxycitric acids to their lactones on heating the above plant sources is deliberated. The Hydrolysis of hydroxycitric acid lactones in aqueous solution is reported for the first time. |
| doi_str_mv | 10.1002/jssc.201700192 |
| format | Article |
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L.</creatorcontrib><creatorcontrib>Mohan, Moolya</creatorcontrib><creatorcontrib>Joseph, David</creatorcontrib><creatorcontrib>Haleema, Simimole</creatorcontrib><creatorcontrib>Aboul‐Enein, Hassan Y.</creatorcontrib><creatorcontrib>Ibnusaud, Ibrahim</creatorcontrib><title>Capillary zone electrophorsis for the analysis of naturally occurring 2‐hydroxycitric acids and their lactones</title><title>Journal of separation science</title><addtitle>J Sep Sci</addtitle><description>A simple capillary zone electrophoresis method with direct ultraviolet detection has been developed for the analysis of naturally occurring diastereomeric 2‐hydroxycitric acid lactones. Using 50 mM sodium phosphate buffer of pH 7, a baseline resolution Rs > 3.0 was observed for all organic acids selected for the present study. This method was employed for the quantitative determination of title acids present in the plant sources namely Garcinia cambogia fruit rinds and Hibiscus sabdariffa calyx. Conversion of 2‐hydroxycitric acids to their lactones on heating the above plant sources is deliberated. The Hydrolysis of hydroxycitric acid lactones in aqueous solution is reported for the first time.</description><subject>2‐hydroxycitric acids</subject><subject>Acids</subject><subject>capillary electrophoresis</subject><subject>Citrates - isolation & purification</subject><subject>Electrophoresis, Capillary</subject><subject>Garcinia - chemistry</subject><subject>garcinia acid</subject><subject>Hibiscus - chemistry</subject><subject>hibiscus acid</subject><subject>Hibiscus sabdariffa</subject><subject>Hydrolysis</subject><subject>lactone hydrolysis</subject><subject>Lactones</subject><subject>Lactones - isolation & purification</subject><subject>Organic acids</subject><subject>Plant Extracts - chemistry</subject><subject>Sodium phosphate</subject><subject>Ultraviolet</subject><issn>1615-9306</issn><issn>1615-9314</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkb1u2zAUhYkiQZ24XTsWBLJ0scN_iWNhtGmCABmSzAJNXdU0aFElJSTq1EfIM-ZJQsGJhy6ZeEF851ycexD6QsmSEsLOtynZJSO0IIRq9gGdUEXlQnMqjg4zUTN0mtI2I0WpyUc0Y6XiinJ1grqV6Zz3Jo74b2gBgwfbx9BtQkwu4SZE3G8Am9b4cfoIDW5NP0Tj_YiDtUOMrv2N2fO_p81Yx_A4WtdHZ7Gxrk5ZV096F7E3ts8L0id03Bif4PPrO0f3P3_crX4trm8uLlffrxdWEMkXZaGAi5pIkLWqCW-0JoYJwRTUWlLF1kJBjmaV1g3htCxhzUBrKzhQqRo-R9_2vl0MfwZIfbVzyUKO2kIYUkU1ZVQLKsqMnv2HbsMQc-KJ4kQzKYoiU8s9ZWNIKUJTddHt8uEqSqqpi2rqojp0kQVfX22H9Q7qA_52_AyIPfDgPIzv2FVXt7crKQXnL1YQlnw</recordid><startdate>201708</startdate><enddate>201708</enddate><creator>Abhijith, B. 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L. ; Mohan, Moolya ; Joseph, David ; Haleema, Simimole ; Aboul‐Enein, Hassan Y. ; Ibnusaud, Ibrahim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4053-876e34d05e5d6d03f990a24426ed95162b46e930c699f03188eb2e99c43e156f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>2‐hydroxycitric acids</topic><topic>Acids</topic><topic>capillary electrophoresis</topic><topic>Citrates - isolation & purification</topic><topic>Electrophoresis, Capillary</topic><topic>Garcinia - chemistry</topic><topic>garcinia acid</topic><topic>Hibiscus - chemistry</topic><topic>hibiscus acid</topic><topic>Hibiscus sabdariffa</topic><topic>Hydrolysis</topic><topic>lactone hydrolysis</topic><topic>Lactones</topic><topic>Lactones - isolation & purification</topic><topic>Organic acids</topic><topic>Plant Extracts - chemistry</topic><topic>Sodium phosphate</topic><topic>Ultraviolet</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Abhijith, B. L.</creatorcontrib><creatorcontrib>Mohan, Moolya</creatorcontrib><creatorcontrib>Joseph, David</creatorcontrib><creatorcontrib>Haleema, Simimole</creatorcontrib><creatorcontrib>Aboul‐Enein, Hassan Y.</creatorcontrib><creatorcontrib>Ibnusaud, Ibrahim</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of separation science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Abhijith, B. 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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | 2‐hydroxycitric acids Acids capillary electrophoresis Citrates - isolation & purification Electrophoresis, Capillary Garcinia - chemistry garcinia acid Hibiscus - chemistry hibiscus acid Hibiscus sabdariffa Hydrolysis lactone hydrolysis Lactones Lactones - isolation & purification Organic acids Plant Extracts - chemistry Sodium phosphate Ultraviolet |
| title | Capillary zone electrophorsis for the analysis of naturally occurring 2‐hydroxycitric acids and their lactones |
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