Hypoxia and inflammation in the release of VEGF and interleukins from human retinal pigment epithelial cells

Purpose Retinal diseases are closely associated with both decreased oxygenation and increased inflammation. It is not known if hypoxia-induced vascular endothelial growth factor (VEGF) expression in the retina itself evokes inflammation, or whether inflammation is a prerequisite for the development...

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Veröffentlicht in:	Graefe's archive for clinical and experimental ophthalmology 2017-09, Vol.255 (9), p.1757-1762
Hauptverfasser:	Arjamaa, Olli, Aaltonen, Vesa, Piippo, Niina, Csont, Tamás, Petrovski, Goran, Kaarniranta, Kai, Kauppinen, Anu
Format:	Artikel
Sprache:	eng
Schlagworte:	Basic Science Enzyme-linked immunosorbent assay Epithelium Hypoxia Inflammation Interleukin 1 Interleukin 18 Interleukin 6 Interleukin 8 Lipopolysaccharides Medicine Medicine & Public Health Ophthalmology Oxygenation Retina Retinal pigment epithelium Toll-like receptors Vascular endothelial growth factor Vascularization
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