ERAAs for menopause treatment: Welcome the 'designer estrogens'

Estrogen receptor agonist-antagonists (ERAAs) selectively inhibit or stimulate estrogen-like action in targeted tissues. This review summarizes how ERAAs can be used in combination with an estrogen or alone to treat menopausal symptoms (vasomotor symptoms, genitourinary syndrome of menopause), breas...

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Veröffentlicht in:Cleveland Clinic journal of medicine 2017-06, Vol.84 (6), p.463-470
Hauptverfasser: Hirsch, Heather D, Shih, Elim, Thacker, Holly L
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container_title Cleveland Clinic journal of medicine
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creator Hirsch, Heather D
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description Estrogen receptor agonist-antagonists (ERAAs) selectively inhibit or stimulate estrogen-like action in targeted tissues. This review summarizes how ERAAs can be used in combination with an estrogen or alone to treat menopausal symptoms (vasomotor symptoms, genitourinary syndrome of menopause), breast cancer or the risk of breast cancer, osteopenia, osteoporosis, and other female midlife concerns.
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subjects Bone Diseases, Metabolic - drug therapy
Breast Neoplasms - drug therapy
Drug Therapy, Combination
Estrogens - pharmacology
Female
Hot Flashes - drug therapy
Humans
Menopause - physiology
Selective Estrogen Receptor Modulators - pharmacology
Treatment Outcome
title ERAAs for menopause treatment: Welcome the 'designer estrogens'
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