KNDy neurone activation prior to the LH surge of the ewe is disrupted by LPS

In the ewe, steroid hormones act on the hypothalamic arcuate nucleus (ARC) to initiate the GnRH/LH surge. Within the ARC, steroid signal transduction may be mediated by estrogen receptive dopamine-, β-endorphin- or neuropeptide Y (NPY)-expressing cells, as well as those co-localising kisspeptin, neu...

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Veröffentlicht in:	Reproduction (Cambridge, England) England), 2017-09, Vol.154 (3), p.281-292
Hauptverfasser:	Fergani, C, Routly, J E, Jones, D N, Pickavance, L C, Smith, R F, Dobson, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arcuate Nucleus of Hypothalamus - cytology Arcuate Nucleus of Hypothalamus - drug effects Arcuate Nucleus of Hypothalamus - metabolism Arcuate Nucleus of Hypothalamus - secretion Crosses, Genetic Dynorphins - blood Dynorphins - metabolism Dynorphins - secretion Female Fluorescent Antibody Technique Follicular Phase - blood Follicular Phase - drug effects Follicular Phase - metabolism Gonadotropin-Releasing Hormone - blood Gonadotropin-Releasing Hormone - metabolism Gonadotropin-Releasing Hormone - secretion Immunohistochemistry Injections, Intravenous Kisspeptins - blood Kisspeptins - metabolism Kisspeptins - secretion Lipopolysaccharides - administration & dosage Lipopolysaccharides - toxicity Luteinizing Hormone - blood Luteinizing Hormone - metabolism Luteinizing Hormone - secretion Nerve Tissue Proteins - blood Nerve Tissue Proteins - metabolism Nerve Tissue Proteins - secretion Neurokinin B - blood Neurokinin B - metabolism Neurokinin B - secretion Neurons - cytology Neurons - drug effects Neurons - metabolism Neurons - secretion Ovary - cytology Ovary - drug effects Ovary - physiology Ovulation - blood Ovulation - drug effects Ovulation - metabolism Pituitary Gland - cytology Pituitary Gland - drug effects Pituitary Gland - metabolism Pituitary Gland - secretion Sheep, Domestic
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