Quantitative proteomics: challenges and opportunities in basic and applied research

In their Perspective, Schubert et al . discuss developments and challenges in mass-spectrometry-based proteomics technology in the past decade and explore its role in molecular systems biology, clinical research and personalized medicine. In this Perspective, we discuss developments in mass-spectrom...

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Veröffentlicht in:Nature protocols 2017-07, Vol.12 (7), p.1289-1294
Hauptverfasser: Schubert, Olga T, Röst, Hannes L, Collins, Ben C, Rosenberger, George, Aebersold, Ruedi
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container_issue 7
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container_title Nature protocols
container_volume 12
creator Schubert, Olga T
Röst, Hannes L
Collins, Ben C
Rosenberger, George
Aebersold, Ruedi
description In their Perspective, Schubert et al . discuss developments and challenges in mass-spectrometry-based proteomics technology in the past decade and explore its role in molecular systems biology, clinical research and personalized medicine. In this Perspective, we discuss developments in mass-spectrometry-based proteomic technology over the past decade from the viewpoint of our laboratory. We also reflect on existing challenges and limitations, and explore the current and future roles of quantitative proteomics in molecular systems biology, clinical research and personalized medicine.
doi_str_mv 10.1038/nprot.2017.040
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subjects 631/1647/296
631/45/475/2290
Analytical Chemistry
Biological Techniques
Biology
Clinical Laboratory Techniques - methods
Computational Biology/Bioinformatics
Forecasts and trends
Humans
Innovations
Life Sciences
Mass Spectrometry - methods
Medicine
Microarrays
Molecular biology
Organic Chemistry
perspective
Precision medicine
Proteomics
Proteomics - methods
Proteomics - trends
Spectrometry
Spectroscopy
Systems Biology - methods
title Quantitative proteomics: challenges and opportunities in basic and applied research
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