Effect of interferon-based and -free therapy on early occurrence and recurrence of hepatocellular carcinoma in chronic hepatitis C

[Display omitted] •The risks of early HCC after viral eradication were similar between IFN-based and-free therapies.•Post-treatment levels of WFA+M2BP may be helpful for screening biomarkers to assess the risks of HCC.•Post-treatment WFA+M2BP was identified independently from liver fibrosis as a fac...

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Veröffentlicht in:	Journal of hepatology 2017-11, Vol.67 (5), p.933-939
Hauptverfasser:	Nagata, Hiroko, Nakagawa, Mina, Asahina, Yasuhiro, Sato, Ayako, Asano, Yu, Tsunoda, Tomoyuki, Miyoshi, Masato, Kaneko, Shun, Otani, Satoshi, Kawai-Kitahata, Fukiko, Murakawa, Miyako, Nitta, Sayuri, Itsui, Yasuhiro, Azuma, Seishin, Kakinuma, Sei, Nouchi, Toshihiko, Sakai, Hideki, Tomita, Makoto, Watanabe, Mamoru
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged alpha-Fetoproteins - analysis Antigens, Neoplasm - analysis Antiviral agents Antiviral Agents - administration & dosage Biomarkers Biomarkers, Tumor - analysis Carcinoma, Hepatocellular - epidemiology Carcinoma, Hepatocellular - pathology Carcinoma, Hepatocellular - physiopathology Carcinoma, Hepatocellular - prevention & control Chronic illnesses Direct-acting antiviral agent Eradication Female Fibrosis Gastroenterology and Hepatology HCC occurrence HCC recurrence Hepatitis Hepatitis C Hepatitis C, Chronic - complications Hepatitis C, Chronic - drug therapy Hepatocarcinogenesis Hepatocellular carcinoma Humans Interferon Interferons - administration & dosage Japan - epidemiology Liver cancer Liver Neoplasms - etiology Liver Neoplasms - pathology Liver Neoplasms - physiopathology Liver Neoplasms - prevention & control Medical treatment Membrane Glycoproteins - analysis Middle Aged Multivariate analysis Neoplasm Recurrence, Local - diagnosis Neoplasm Recurrence, Local - etiology Neoplasm Recurrence, Local - virology Patients Plant Lectins - analysis Receptors, N-Acetylglucosamine - analysis Risk Assessment - methods Risk Factors Wisteria floribunda agglutinin positive Mac-2 binding protein
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