C1q/TNF-related protein 1 promotes endothelial barrier dysfunction under disturbed flow

Endothelial hyper-permeability is a major determinant factor that contributes to the accelerated development of atherosclerotic lesions at hemodynamically disturbed sites. Previously, we showed that C1q/TNF related protein (CTRP) 1 promotes endothelium-leukocyte interactions and inflammatory respons...

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Veröffentlicht in:	Biochemical and biophysical research communications 2017-08, Vol.490 (2), p.580-586
Hauptverfasser:	Liu, Zhu Hui, Li, Chang, Chen, Jia Wei, Shen, Ying, Gao, Jie, Shen, Wei Feng, Zhang, Rui Yan, Wang, Xiao Qun, Lu, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipokines - analysis Adipokines - genetics Adipokines - metabolism Animals Aorta - physiology Blood Flow Velocity Capillary Permeability CTRP1 Disturbed flow Endothelial cell Endothelial Cells - cytology Endothelial Cells - metabolism Endothelium, Vascular - cytology Endothelium, Vascular - physiology Gene Knock-In Techniques Human Umbilical Vein Endothelial Cells Mice, Knockout Permeability Proteins - analysis Proteins - genetics Proteins - metabolism Vascular Endothelial Growth Factor Receptor-2 - metabolism
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