Chronic liver disease is a risk factor for malnutrition and growth retardation in children
Background: Despite distinct advancements in nutritional therapy, malnutrition and growth retardation remain inevitable consequences of chronic liver disease. The global prevalence of chronic liver disease in children is about 3%, with a quarter undernourished. Malnutrition itself is a negative prog...
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| Veröffentlicht in: | Asia Pacific Journal of Clinical Nutrition 2017-06, Vol.26 (S1), p.s57-s60 |
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| container_title | Asia Pacific Journal of Clinical Nutrition |
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| creator | Widodo, Ariani Dewi Soelaeman, Eva J Dwinanda, Novitria Narendraswari, Prajnya P Purnomo, Budi |
| description | Background: Despite distinct advancements in nutritional therapy, malnutrition and growth retardation remain inevitable consequences of chronic liver disease. The global prevalence of chronic liver disease in children is about 3%, with a quarter undernourished. Malnutrition itself is a negative prognostic indicator of survival. Further research is necessary for delivering adequate nutritional support to reduce morbidity and mortality. Objective: To evaluate the nutritional status and growth of children with chronic liver disease and its contributing factors. Methods and Study Design: Data were gathered about 21 children aged 7 months to 13.3 years diagnosed with chronic liver disease at Harapan Kita Women and Children Hospital between November 2014 and February 2016. Physical growth and nutritional status were evaluated using anthropometric percentiles and z-scores. Laboratory measurements were made on their first visit. Results: The mean age of participants was 43.9±47.4 months. Mean weight was 13.4±9.31 kg, and mean length/height was 88.8±27.7 cm. Ten (47.6%) and 3 (14.3%) patients had moderate or severe undernutrition, respectively, and 38% (8 patients) had growth retardation. Of those with good nutritional status, 62.5% were older than 5 years. Malnutrition was correlated with growth failure, a low serum albumin, and elevated aspartate transaminase (p＜0.05 in all cases). Conclusion: Early diagnosis of malnutrition should encourage nutritional support, delay illness progression and increase survival in children with chronic liver disease. |
| doi_str_mv | 10.6133/apjcn.062017.s10 |
| format | Article |
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The global prevalence of chronic liver disease in children is about 3%, with a quarter undernourished. Malnutrition itself is a negative prognostic indicator of survival. Further research is necessary for delivering adequate nutritional support to reduce morbidity and mortality. Objective: To evaluate the nutritional status and growth of children with chronic liver disease and its contributing factors. Methods and Study Design: Data were gathered about 21 children aged 7 months to 13.3 years diagnosed with chronic liver disease at Harapan Kita Women and Children Hospital between November 2014 and February 2016. Physical growth and nutritional status were evaluated using anthropometric percentiles and z-scores. Laboratory measurements were made on their first visit. Results: The mean age of participants was 43.9±47.4 months. Mean weight was 13.4±9.31 kg, and mean length/height was 88.8±27.7 cm. Ten (47.6%) and 3 (14.3%) patients had moderate or severe undernutrition, respectively, and 38% (8 patients) had growth retardation. Of those with good nutritional status, 62.5% were older than 5 years. Malnutrition was correlated with growth failure, a low serum albumin, and elevated aspartate transaminase (p＜0.05 in all cases). Conclusion: Early diagnosis of malnutrition should encourage nutritional support, delay illness progression and increase survival in children with chronic liver disease.</description><identifier>ISSN: 0964-7058</identifier><identifier>EISSN: 1440-6047</identifier><identifier>DOI: 10.6133/apjcn.062017.s10</identifier><identifier>PMID: 28625038</identifier><language>eng</language><publisher>Clayton, Vic: HEC Press</publisher><subject>Age ; Child ; Child Nutrition Disorders - etiology ; Child, Preschool ; Children ; Children & youth ; Developing countries ; Diagnosis ; Diseases ; Dwarfism ; End Stage Liver Disease - complications ; Family medical history ; Female ; Growth ; Growth Disorders - etiology ; Hepatology ; Hospitals ; Humans ; Infant ; LDCs ; Liver ; Liver cirrhosis ; Liver diseases ; Male ; Malnutrition ; Malnutrition in children ; Measurement ; Medical prognosis ; Metabolism ; Morbidity ; Mortality ; Nutrition ; Pediatrics ; Prevention ; Risk Factors ; Treatment ; Womens health</subject><ispartof>Asia Pacific Journal of Clinical Nutrition, 2017-06, Vol.26 (S1), p.s57-s60</ispartof><rights>Copyright HEC Press Jun 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a428t-f65512073d3577f92fc9e6b7c77a3b2d19f44fa0510cdfee361cd55a8194f40e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28625038$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Widodo, Ariani Dewi</creatorcontrib><creatorcontrib>Soelaeman, Eva J</creatorcontrib><creatorcontrib>Dwinanda, Novitria</creatorcontrib><creatorcontrib>Narendraswari, Prajnya P</creatorcontrib><creatorcontrib>Purnomo, Budi</creatorcontrib><title>Chronic liver disease is a risk factor for malnutrition and growth retardation in children</title><title>Asia Pacific Journal of Clinical Nutrition</title><addtitle>Asia Pac J Clin Nutr</addtitle><description>Background: Despite distinct advancements in nutritional therapy, malnutrition and growth retardation remain inevitable consequences of chronic liver disease. The global prevalence of chronic liver disease in children is about 3%, with a quarter undernourished. Malnutrition itself is a negative prognostic indicator of survival. Further research is necessary for delivering adequate nutritional support to reduce morbidity and mortality. Objective: To evaluate the nutritional status and growth of children with chronic liver disease and its contributing factors. Methods and Study Design: Data were gathered about 21 children aged 7 months to 13.3 years diagnosed with chronic liver disease at Harapan Kita Women and Children Hospital between November 2014 and February 2016. Physical growth and nutritional status were evaluated using anthropometric percentiles and z-scores. Laboratory measurements were made on their first visit. Results: The mean age of participants was 43.9±47.4 months. Mean weight was 13.4±9.31 kg, and mean length/height was 88.8±27.7 cm. Ten (47.6%) and 3 (14.3%) patients had moderate or severe undernutrition, respectively, and 38% (8 patients) had growth retardation. Of those with good nutritional status, 62.5% were older than 5 years. Malnutrition was correlated with growth failure, a low serum albumin, and elevated aspartate transaminase (p＜0.05 in all cases). Conclusion: Early diagnosis of malnutrition should encourage nutritional support, delay illness progression and increase survival in children with chronic liver disease.</description><subject>Age</subject><subject>Child</subject><subject>Child Nutrition Disorders - etiology</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Children & youth</subject><subject>Developing countries</subject><subject>Diagnosis</subject><subject>Diseases</subject><subject>Dwarfism</subject><subject>End Stage Liver Disease - complications</subject><subject>Family medical history</subject><subject>Female</subject><subject>Growth</subject><subject>Growth Disorders - etiology</subject><subject>Hepatology</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Infant</subject><subject>LDCs</subject><subject>Liver</subject><subject>Liver cirrhosis</subject><subject>Liver diseases</subject><subject>Male</subject><subject>Malnutrition</subject><subject>Malnutrition in children</subject><subject>Measurement</subject><subject>Medical prognosis</subject><subject>Metabolism</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>Nutrition</subject><subject>Pediatrics</subject><subject>Prevention</subject><subject>Risk Factors</subject><subject>Treatment</subject><subject>Womens health</subject><issn>0964-7058</issn><issn>1440-6047</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkc2LFDEQxYMo7uzq3ZMEvHjpsfLdOcqgrrDgZb14CZl87GTsTsak28X_3m5nZVFCKCr141F5D6FXBLaSMPbOno4ub0FSIGrbCDxBG8I5dBK4eoo2oCXvFIj-Al22dgQAxkE8Rxe0l1QA6zfo2-5QS04OD-lnqNinFmwLODVscU3tO47WTaXiuNzRDnmeappSydhmj-9quZ8OuIbJVm__PKeM3SENvob8Aj2Ldmjh5UO9Ql8_frjdXXc3Xz593r2_6Syn_dRFKQShoJhnQqmoaXQ6yL1ySlm2p57oyHm0IAg4H0NgkjgvhO2J5pFDYFfo7Vn3VMuPObTJjKm5MAw2hzI3QzQhRGtK6YK--Q89lrnmZbuV4r3QwPuFev1AzfsxeHOqabT1l_nr2gLcnoE6psm4MgzBrb9vRzs1szhY3cGkvHi2zku9M74kQ8AwRuTjQBMltFJcMk6oYIvs9VnWptXkx93WHNcYzZozyHPplwNA_m2aUKZJYL8BQC6g7Q</recordid><startdate>201706</startdate><enddate>201706</enddate><creator>Widodo, Ariani Dewi</creator><creator>Soelaeman, Eva J</creator><creator>Dwinanda, Novitria</creator><creator>Narendraswari, Prajnya P</creator><creator>Purnomo, Budi</creator><general>HEC Press</general><scope>188</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BVBZV</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>201706</creationdate><title>Chronic liver disease is a risk factor for malnutrition and growth retardation in children</title><author>Widodo, Ariani Dewi ; Soelaeman, Eva J ; Dwinanda, Novitria ; Narendraswari, Prajnya P ; Purnomo, Budi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a428t-f65512073d3577f92fc9e6b7c77a3b2d19f44fa0510cdfee361cd55a8194f40e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Age</topic><topic>Child</topic><topic>Child Nutrition Disorders - etiology</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Children & youth</topic><topic>Developing countries</topic><topic>Diagnosis</topic><topic>Diseases</topic><topic>Dwarfism</topic><topic>End Stage Liver Disease - complications</topic><topic>Family medical history</topic><topic>Female</topic><topic>Growth</topic><topic>Growth Disorders - etiology</topic><topic>Hepatology</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Infant</topic><topic>LDCs</topic><topic>Liver</topic><topic>Liver cirrhosis</topic><topic>Liver diseases</topic><topic>Male</topic><topic>Malnutrition</topic><topic>Malnutrition in children</topic><topic>Measurement</topic><topic>Medical prognosis</topic><topic>Metabolism</topic><topic>Morbidity</topic><topic>Mortality</topic><topic>Nutrition</topic><topic>Pediatrics</topic><topic>Prevention</topic><topic>Risk Factors</topic><topic>Treatment</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Widodo, Ariani Dewi</creatorcontrib><creatorcontrib>Soelaeman, Eva J</creatorcontrib><creatorcontrib>Dwinanda, Novitria</creatorcontrib><creatorcontrib>Narendraswari, Prajnya P</creatorcontrib><creatorcontrib>Purnomo, Budi</creatorcontrib><collection>Airiti Library</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>East & South Asia Database</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Asia Pacific Journal of Clinical Nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Widodo, Ariani Dewi</au><au>Soelaeman, Eva J</au><au>Dwinanda, Novitria</au><au>Narendraswari, Prajnya P</au><au>Purnomo, Budi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chronic liver disease is a risk factor for malnutrition and growth retardation in children</atitle><jtitle>Asia Pacific Journal of Clinical Nutrition</jtitle><addtitle>Asia Pac J Clin Nutr</addtitle><date>2017-06</date><risdate>2017</risdate><volume>26</volume><issue>S1</issue><spage>s57</spage><epage>s60</epage><pages>s57-s60</pages><issn>0964-7058</issn><eissn>1440-6047</eissn><abstract>Background: Despite distinct advancements in nutritional therapy, malnutrition and growth retardation remain inevitable consequences of chronic liver disease. The global prevalence of chronic liver disease in children is about 3%, with a quarter undernourished. Malnutrition itself is a negative prognostic indicator of survival. Further research is necessary for delivering adequate nutritional support to reduce morbidity and mortality. Objective: To evaluate the nutritional status and growth of children with chronic liver disease and its contributing factors. Methods and Study Design: Data were gathered about 21 children aged 7 months to 13.3 years diagnosed with chronic liver disease at Harapan Kita Women and Children Hospital between November 2014 and February 2016. Physical growth and nutritional status were evaluated using anthropometric percentiles and z-scores. Laboratory measurements were made on their first visit. Results: The mean age of participants was 43.9±47.4 months. Mean weight was 13.4±9.31 kg, and mean length/height was 88.8±27.7 cm. Ten (47.6%) and 3 (14.3%) patients had moderate or severe undernutrition, respectively, and 38% (8 patients) had growth retardation. Of those with good nutritional status, 62.5% were older than 5 years. Malnutrition was correlated with growth failure, a low serum albumin, and elevated aspartate transaminase (p＜0.05 in all cases). Conclusion: Early diagnosis of malnutrition should encourage nutritional support, delay illness progression and increase survival in children with chronic liver disease.</abstract><cop>Clayton, Vic</cop><pub>HEC Press</pub><pmid>28625038</pmid><doi>10.6133/apjcn.062017.s10</doi><tpages>4</tpages></addata></record> |
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| subjects | Age Child Child Nutrition Disorders - etiology Child, Preschool Children Children & youth Developing countries Diagnosis Diseases Dwarfism End Stage Liver Disease - complications Family medical history Female Growth Growth Disorders - etiology Hepatology Hospitals Humans Infant LDCs Liver Liver cirrhosis Liver diseases Male Malnutrition Malnutrition in children Measurement Medical prognosis Metabolism Morbidity Mortality Nutrition Pediatrics Prevention Risk Factors Treatment Womens health |
| title | Chronic liver disease is a risk factor for malnutrition and growth retardation in children |
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