Clean catch urine collection: Time taken and diagnostic implication. A prospective observational study

Aim Clean catch urine (CCU) collection is commonly used in pre‐continent children. CCU can be time‐consuming and specimens may be contaminated. Our aim was to determine the time taken for CCU attempts and to describe the success of this method in diagnosing or excluding urinary tract infection. Meth...

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Veröffentlicht in:Journal of paediatrics and child health 2017-10, Vol.53 (10), p.970-975
Hauptverfasser: Tosif, Shidan, Kaufman, Jonathan, Fitzpatrick, Patrick, Hopper, Sandy M, Hoq, Monsurul, Donath, Susan, Babl, Franz E
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container_end_page 975
container_issue 10
container_start_page 970
container_title Journal of paediatrics and child health
container_volume 53
creator Tosif, Shidan
Kaufman, Jonathan
Fitzpatrick, Patrick
Hopper, Sandy M
Hoq, Monsurul
Donath, Susan
Babl, Franz E
description Aim Clean catch urine (CCU) collection is commonly used in pre‐continent children. CCU can be time‐consuming and specimens may be contaminated. Our aim was to determine the time taken for CCU attempts and to describe the success of this method in diagnosing or excluding urinary tract infection. Methods Prospective observational study of CCU in pre‐continent children aged 2–48 months in the emergency department. Time taken until urine collection, ‘successful’ (voided and caught), ‘missed’ (voided not caught) or the procedure ‘stopped’, were recorded and urine culture results analysed. Results Two hundred and seventeen children (131 (60%) male) were enrolled. There were a total of 247 attempts at CCU. For the first attempt, the median collecting time was 30.5 min (interquartile range (IQR) 11–66). Outcome was ‘successful’ in 64% (95% confidence intervals (CI) 58–70%), ‘missed’ in 16% (95% CI 11–20%) and ‘stopped’ in 20% (95% CI 15–26%). Median time if ‘successful’ was 25 min (IQR 7–46.5), ‘missed’ 27 min (IQR 11.6–59) and 71 min (IQR 42.5–93) when ‘stopped’. One hundred and sixty children had successful CCU collection, 129 were sent for culture. Fifty of 129 (39%) cultures were contaminated. If all urine specimens caught were sent for culture, the estimated yield of an uncontaminated urine specimen was 45%. Contamination was not related to time taken for CCU. Conclusions CCU is time‐consuming, frequently unsuccessful and contaminated, resulting in a low overall diagnostic yield. Clinicians could expect a 45% chance of obtaining a definitive urine sample from this method overall.
doi_str_mv 10.1111/jpc.13595
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A prospective observational study</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Tosif, Shidan ; Kaufman, Jonathan ; Fitzpatrick, Patrick ; Hopper, Sandy M ; Hoq, Monsurul ; Donath, Susan ; Babl, Franz E</creator><creatorcontrib>Tosif, Shidan ; Kaufman, Jonathan ; Fitzpatrick, Patrick ; Hopper, Sandy M ; Hoq, Monsurul ; Donath, Susan ; Babl, Franz E</creatorcontrib><description>Aim Clean catch urine (CCU) collection is commonly used in pre‐continent children. CCU can be time‐consuming and specimens may be contaminated. Our aim was to determine the time taken for CCU attempts and to describe the success of this method in diagnosing or excluding urinary tract infection. Methods Prospective observational study of CCU in pre‐continent children aged 2–48 months in the emergency department. Time taken until urine collection, ‘successful’ (voided and caught), ‘missed’ (voided not caught) or the procedure ‘stopped’, were recorded and urine culture results analysed. Results Two hundred and seventeen children (131 (60%) male) were enrolled. There were a total of 247 attempts at CCU. For the first attempt, the median collecting time was 30.5 min (interquartile range (IQR) 11–66). Outcome was ‘successful’ in 64% (95% confidence intervals (CI) 58–70%), ‘missed’ in 16% (95% CI 11–20%) and ‘stopped’ in 20% (95% CI 15–26%). Median time if ‘successful’ was 25 min (IQR 7–46.5), ‘missed’ 27 min (IQR 11.6–59) and 71 min (IQR 42.5–93) when ‘stopped’. One hundred and sixty children had successful CCU collection, 129 were sent for culture. Fifty of 129 (39%) cultures were contaminated. If all urine specimens caught were sent for culture, the estimated yield of an uncontaminated urine specimen was 45%. Contamination was not related to time taken for CCU. Conclusions CCU is time‐consuming, frequently unsuccessful and contaminated, resulting in a low overall diagnostic yield. Clinicians could expect a 45% chance of obtaining a definitive urine sample from this method overall.</description><identifier>ISSN: 1034-4810</identifier><identifier>EISSN: 1440-1754</identifier><identifier>DOI: 10.1111/jpc.13595</identifier><identifier>PMID: 28618045</identifier><language>eng</language><publisher>Australia: John Wiley &amp; Sons Australia, Ltd</publisher><subject>Child, Preschool ; Diagnostic tests ; emergency medicine ; Female ; general paediatrics ; Humans ; Infant ; Male ; Medical diagnosis ; nephrology/renal ; Observational studies ; Pediatrics ; Prospective Studies ; Specimen Handling ; Time Factors ; urinary tract infection ; Urinary tract infections ; Urinary Tract Infections - diagnosis ; Urine ; Urine Specimen Collection - methods</subject><ispartof>Journal of paediatrics and child health, 2017-10, Vol.53 (10), p.970-975</ispartof><rights>2017 Paediatrics and Child Health Division (The Royal Australasian College of Physicians)</rights><rights>2017 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).</rights><rights>2017 Paediatrics and Child Health Division (Royal Australasian College of Physicians)</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3885-2a3f5bbe6c4e1722e2a591c80528c760fde95776c14d3f527c674d45a9c77f703</citedby><cites>FETCH-LOGICAL-c3885-2a3f5bbe6c4e1722e2a591c80528c760fde95776c14d3f527c674d45a9c77f703</cites><orcidid>0000-0003-0022-1009</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjpc.13595$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjpc.13595$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28618045$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tosif, Shidan</creatorcontrib><creatorcontrib>Kaufman, Jonathan</creatorcontrib><creatorcontrib>Fitzpatrick, Patrick</creatorcontrib><creatorcontrib>Hopper, Sandy M</creatorcontrib><creatorcontrib>Hoq, Monsurul</creatorcontrib><creatorcontrib>Donath, Susan</creatorcontrib><creatorcontrib>Babl, Franz E</creatorcontrib><title>Clean catch urine collection: Time taken and diagnostic implication. A prospective observational study</title><title>Journal of paediatrics and child health</title><addtitle>J Paediatr Child Health</addtitle><description>Aim Clean catch urine (CCU) collection is commonly used in pre‐continent children. CCU can be time‐consuming and specimens may be contaminated. Our aim was to determine the time taken for CCU attempts and to describe the success of this method in diagnosing or excluding urinary tract infection. Methods Prospective observational study of CCU in pre‐continent children aged 2–48 months in the emergency department. Time taken until urine collection, ‘successful’ (voided and caught), ‘missed’ (voided not caught) or the procedure ‘stopped’, were recorded and urine culture results analysed. Results Two hundred and seventeen children (131 (60%) male) were enrolled. There were a total of 247 attempts at CCU. For the first attempt, the median collecting time was 30.5 min (interquartile range (IQR) 11–66). Outcome was ‘successful’ in 64% (95% confidence intervals (CI) 58–70%), ‘missed’ in 16% (95% CI 11–20%) and ‘stopped’ in 20% (95% CI 15–26%). Median time if ‘successful’ was 25 min (IQR 7–46.5), ‘missed’ 27 min (IQR 11.6–59) and 71 min (IQR 42.5–93) when ‘stopped’. One hundred and sixty children had successful CCU collection, 129 were sent for culture. Fifty of 129 (39%) cultures were contaminated. If all urine specimens caught were sent for culture, the estimated yield of an uncontaminated urine specimen was 45%. Contamination was not related to time taken for CCU. Conclusions CCU is time‐consuming, frequently unsuccessful and contaminated, resulting in a low overall diagnostic yield. Clinicians could expect a 45% chance of obtaining a definitive urine sample from this method overall.</description><subject>Child, Preschool</subject><subject>Diagnostic tests</subject><subject>emergency medicine</subject><subject>Female</subject><subject>general paediatrics</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>nephrology/renal</subject><subject>Observational studies</subject><subject>Pediatrics</subject><subject>Prospective Studies</subject><subject>Specimen Handling</subject><subject>Time Factors</subject><subject>urinary tract infection</subject><subject>Urinary tract infections</subject><subject>Urinary Tract Infections - diagnosis</subject><subject>Urine</subject><subject>Urine Specimen Collection - methods</subject><issn>1034-4810</issn><issn>1440-1754</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kD1PwzAQhi0EoqUw8AeQJRYY0tqJHSdsVcSnKsFQ5shxLuDifBAnRf33uE1hQMLLWbrnXt09CJ1TMqXuzVaNmtKAx_wAjSljxKOCs0P3JwHzWETJCJ1YuyKE-JxHx2jkRyGNCONjVCQGZIWV7NQ77ltdAVa1MaA6XVc3eKlLwJ38gArLKse5lm9VbTutsC4bo92Yw6Z4jpu2ts12ag24ziy0611LGmy7Pt-coqNCGgtn-zpBr3e3y-TBWzzfPybzhaeCKOKeL4OCZxmEigEVvg--5DFVEeF-pERIihxiLkSoKMsd6QsVCpYzLmMlRCFIMEFXQ67b57MH26WltgqMkRXUvU1pTImIGRPMoZd_0FXdt27jLcVC587JctT1QCl3oG2hSJtWl7LdpJSkW_mpk5_u5Dv2Yp_YZyXkv-SPbQfMBuBLG9j8n5Q-vSRD5DdpRI2y</recordid><startdate>201710</startdate><enddate>201710</enddate><creator>Tosif, Shidan</creator><creator>Kaufman, Jonathan</creator><creator>Fitzpatrick, Patrick</creator><creator>Hopper, Sandy M</creator><creator>Hoq, Monsurul</creator><creator>Donath, Susan</creator><creator>Babl, Franz E</creator><general>John Wiley &amp; Sons Australia, Ltd</general><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-0022-1009</orcidid></search><sort><creationdate>201710</creationdate><title>Clean catch urine collection: Time taken and diagnostic implication. A prospective observational study</title><author>Tosif, Shidan ; Kaufman, Jonathan ; Fitzpatrick, Patrick ; Hopper, Sandy M ; Hoq, Monsurul ; Donath, Susan ; Babl, Franz E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3885-2a3f5bbe6c4e1722e2a591c80528c760fde95776c14d3f527c674d45a9c77f703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Child, Preschool</topic><topic>Diagnostic tests</topic><topic>emergency medicine</topic><topic>Female</topic><topic>general paediatrics</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>Medical diagnosis</topic><topic>nephrology/renal</topic><topic>Observational studies</topic><topic>Pediatrics</topic><topic>Prospective Studies</topic><topic>Specimen Handling</topic><topic>Time Factors</topic><topic>urinary tract infection</topic><topic>Urinary tract infections</topic><topic>Urinary Tract Infections - diagnosis</topic><topic>Urine</topic><topic>Urine Specimen Collection - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tosif, Shidan</creatorcontrib><creatorcontrib>Kaufman, Jonathan</creatorcontrib><creatorcontrib>Fitzpatrick, Patrick</creatorcontrib><creatorcontrib>Hopper, Sandy M</creatorcontrib><creatorcontrib>Hoq, Monsurul</creatorcontrib><creatorcontrib>Donath, Susan</creatorcontrib><creatorcontrib>Babl, Franz E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of paediatrics and child health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tosif, Shidan</au><au>Kaufman, Jonathan</au><au>Fitzpatrick, Patrick</au><au>Hopper, Sandy M</au><au>Hoq, Monsurul</au><au>Donath, Susan</au><au>Babl, Franz E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clean catch urine collection: Time taken and diagnostic implication. A prospective observational study</atitle><jtitle>Journal of paediatrics and child health</jtitle><addtitle>J Paediatr Child Health</addtitle><date>2017-10</date><risdate>2017</risdate><volume>53</volume><issue>10</issue><spage>970</spage><epage>975</epage><pages>970-975</pages><issn>1034-4810</issn><eissn>1440-1754</eissn><abstract>Aim Clean catch urine (CCU) collection is commonly used in pre‐continent children. CCU can be time‐consuming and specimens may be contaminated. Our aim was to determine the time taken for CCU attempts and to describe the success of this method in diagnosing or excluding urinary tract infection. Methods Prospective observational study of CCU in pre‐continent children aged 2–48 months in the emergency department. Time taken until urine collection, ‘successful’ (voided and caught), ‘missed’ (voided not caught) or the procedure ‘stopped’, were recorded and urine culture results analysed. Results Two hundred and seventeen children (131 (60%) male) were enrolled. There were a total of 247 attempts at CCU. For the first attempt, the median collecting time was 30.5 min (interquartile range (IQR) 11–66). Outcome was ‘successful’ in 64% (95% confidence intervals (CI) 58–70%), ‘missed’ in 16% (95% CI 11–20%) and ‘stopped’ in 20% (95% CI 15–26%). Median time if ‘successful’ was 25 min (IQR 7–46.5), ‘missed’ 27 min (IQR 11.6–59) and 71 min (IQR 42.5–93) when ‘stopped’. One hundred and sixty children had successful CCU collection, 129 were sent for culture. Fifty of 129 (39%) cultures were contaminated. If all urine specimens caught were sent for culture, the estimated yield of an uncontaminated urine specimen was 45%. Contamination was not related to time taken for CCU. Conclusions CCU is time‐consuming, frequently unsuccessful and contaminated, resulting in a low overall diagnostic yield. Clinicians could expect a 45% chance of obtaining a definitive urine sample from this method overall.</abstract><cop>Australia</cop><pub>John Wiley &amp; Sons Australia, Ltd</pub><pmid>28618045</pmid><doi>10.1111/jpc.13595</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-0022-1009</orcidid><oa>free_for_read</oa></addata></record>
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subjects Child, Preschool
Diagnostic tests
emergency medicine
Female
general paediatrics
Humans
Infant
Male
Medical diagnosis
nephrology/renal
Observational studies
Pediatrics
Prospective Studies
Specimen Handling
Time Factors
urinary tract infection
Urinary tract infections
Urinary Tract Infections - diagnosis
Urine
Urine Specimen Collection - methods
title Clean catch urine collection: Time taken and diagnostic implication. A prospective observational study
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