Favouring modulation of circulating lipoproteins and lipid loading capacity by direct antiviral agents grazoprevir/elbasvir or ledipasvir/sofosbuvir treatment against chronic HCV infection

ObjectiveLipid homoeostasis is disturbed in patients with HCV infection. Direct-acting antiviral agent (DAA) treatment eradicates chronic HCV viraemia, but the dynamics of lipid components remain elusive. This study investigates the clinical manifestation and mechanistic relevance of plasma triglyce...

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Veröffentlicht in:	Gut 2018-07, Vol.67 (7), p.1342-1350
Hauptverfasser:	Sun, Hung-Yu, Cheng, Pin-Nan, Tseng, Chiung-Ying, Tsai, Wei-Jen, Chiu, Yen-Cheng, Young, Kung-Chia
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral agents Antiviral drugs Apolipoproteins Cholesterol Chronic infection Eradication Fibrosis Genotypes Hepatitis C Insulin resistance Interferon Lipids Lipoproteins Lipoproteins (very low density) Liver Low density lipoprotein Patients Viremia
Online-Zugang:	Volltext
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