CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17–Producing γδ T Cells in Stroke

BACKGROUND AND PURPOSE—Immune-mediated tissue damage after stroke evolves within the first days, and lymphocytes contribute to the secondary injury. Our goal was to identify T-cell subpopulations, which trigger the immune response. METHODS—In a model of experimental stroke, we analyzed the immune ph...

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Veröffentlicht in:	Stroke (1970) 2017-07, Vol.48 (7), p.1957-1965
Hauptverfasser:	Arunachalam, Priyadharshini, Ludewig, Peter, Melich, Patrick, Arumugam, Thiruma Valavan, Gerloff, Christian, Prinz, Immo, Magnus, Tim, Gelderblom, Mathias
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Movement Disease Models, Animal Interleukin-17 - immunology Mice Mice, Inbred C57BL Mice, Transgenic Receptors, CCR6 - immunology Stroke - immunology T-Lymphocyte Subsets - immunology
Online-Zugang:	Volltext
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