Apoptosis Following Cortical Spreading Depression in Juvenile Rats

Repetitive cortical spreading depression (CSD) can lead to cell death in immature brain tissue. Caspases are involved in neuronal cell death in several CSD-related neurological disorders, such as stroke and epilepsy. Yet, whether repetitive CSD itself can induce caspase activation in adult or juveni...

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Veröffentlicht in:	Molecular neurobiology 2018-05, Vol.55 (5), p.4225-4239
Hauptverfasser:	Jahanbazi Jahan-Abad, Ali, Alizadeh, Leila, Sahab Negah, Sajad, Barati, Parastoo, Khaleghi Ghadiri, Maryam, Meuth, Sven G, Kovac, Stjepana, Gorji, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals Apoptosis Brain Brain - enzymology Caspase Caspase-12 Caspase-3 Caspase-8 Caspase-9 Caspases - metabolism Cell Count Cell death Cortical Spreading Depression Endoplasmic reticulum Epilepsy Hippocampus Immunohistochemistry Male Mental depression Neurological diseases Neurons - pathology Rats Rats, Wistar Rodents Somatosensory cortex Western blotting
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