Deficits in temporal processing in mice prenatally exposed to Valproic Acid

Temporal processing in the seconds‐to‐minutes range, known as interval timing, is a crucial cognitive function that requires activation of cortico‐striatal circuits via dopaminergic–glutamatergic pathways. In humans, both children and adults with autism spectrum disorders (ASD) present alterations i...

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Veröffentlicht in:	The European journal of neuroscience 2018-03, Vol.47 (6), p.619-630
Hauptverfasser:	Acosta, Julieta, Campolongo, Marcos A., Höcht, Christian, Depino, Amaicha M., Golombek, Diego A., Agostino, Patricia V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Autism autism spectrum disorder Catecholamines Children Cognitive ability cortico‐striatal circuits Dopamine Dopamine receptors Glutamatergic transmission High-performance liquid chromatography Information processing interval timing Neostriatum Prenatal experience Valproic acid
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