Changes in cortical excitability during paired associative stimulation in Parkinson's disease patients and healthy subjects

•PNS conditioned TMS responses are suppressed during facilitatory PAS intervention.•Inhibition during PAS is impaired in both drug-naïve and treated PD patients.•PAS-related cortical networks are damaged at the clinical onset of the disease.•PAS-related cortical networks are not influenced by subseq...

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Veröffentlicht in:	Neuroscience research 2017-11, Vol.124, p.51-56
Hauptverfasser:	Kačar, Aleksandra, Milanović, Sladjan D., Filipović, Saša R., Ljubisavljević, Miloš R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Afferent inhibition Aged Cortical Excitability Evoked Potentials, Motor Female Humans Male Middle Aged Motor Cortex - physiopathology Neural Inhibition Neuronal Plasticity Paired associative stimulation Parkinson Disease - physiopathology Parkinson’s disease Sensory-motor integration Transcranial Magnetic Stimulation Transcutaneous Electric Nerve Stimulation
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