Potential risks of using cement-augmented screws for spinal fusion in patients with low bone quality

Abstract Background Context Dramatic increases in the average life expectancy have led to increases in the variety of degenerative changes and deformities observed in the aging spine. The elderly population can present challenges for spine surgeons, not only because of increased comorbidities, but also because of the quality of their bones. Pedicle screws are the implants used most commonly in spinal surgery for fixation, but their efficacy depends directly on bone quality. While PMMA-augmented screws represent an alternative for patients with osteoporotic vertebrae, their use has raised some concerns due to the possible association between cement leakages (CLs) and other morbidities. Purpose To analyze potential complications related to the use of cement-augmented screws for spinal fusion and to investigate the effectiveness of using these screws in the treatment of patients with low bone quallity. Study Design/Setting A retrospective single-center study. Patient Sample This study included 313 consecutive patients who underwent spinal fusion using a total of 1780 cement-augmented screws. Methods and Outcome Measures We analyzed potential complications related to the use of cement-augmented screws, including CL, vascular injury, infection, screw extraction problems, revision surgery, and instrument failure. There are no financial conflicts of interest to report. Results A total of 1043 vertebrae were instrumented. CL was observed in 650 vertebrae (62.3%). There were no major clinical complications related to CL, but 2 patients (0.6%) had radicular pain related to CL at the S1 foramina. Of the 13 patients (4.1%) who developed deep infections requiring surgical debridement, 2 with chronic infections had possible spondylitis that required instrument removal. All patients responded well to antibiotic therapy. Revision surgery was performed in 56 patients (17.9%), most of whom had long construction. A total of 180 screws were removed as a result of revision. There were no problems with screw extraction. Conclusion These results demonstrate the efficacy and safety of cement-augmented screws for the treatment of patients with low bone mineral density.