Histone modifications on the promoters of human OCT4 and NANOG genes at the onset of neural differentiation of NT2/D1 cells

Transcription factors OCT4 and NANOG are main constituents of a functional network that controls proliferation and pluripotency maintenance of stem cells as well as early lineage decisions. We investigated expression profiles of OCT4 and NANOG during the early phases of neural differentiation using...

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Veröffentlicht in:	Biochemistry (Moscow) 2017-06, Vol.82 (6), p.715-722
Hauptverfasser:	Topalovic, V., Schwirtlich, M., Stevanovic, M., Mojsin, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Cell Differentiation - drug effects Cell Line Cell lines Cell proliferation Chromatin Decisions Deoxyribonucleic acid Differentiation DNA DNA methylation DNA Methylation - drug effects Enrichment Epigenesis, Genetic - drug effects Exposure Functional anatomy Gene expression Genes Health aspects Histones Histones - genetics Histones - metabolism Humans Immunoprecipitation In vitro methods and tests Life Sciences Maintenance Mathematical models Microbiology Nanog Homeobox Protein - genetics Nanog Homeobox Protein - metabolism Nanostructure Neural circuitry Neurogenesis Neurogenesis - drug effects Neurotrophin 2 Oct-4 protein Octamer Transcription Factor-3 - genetics Octamer Transcription Factor-3 - metabolism Phases Pluripotency Promoters Promoters (Genetics) Protein Processing, Post-Translational - drug effects Proteins Retinoic acid Review Stem cells Stimuli Transcription factors Tretinoin - pharmacology
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