Role of alcohol and marijuana use in the initiation of fatal two-vehicle crashes
Abstract Purpose To assess individual and joint effects of alcohol and marijuana on the initiation of fatal two-vehicle crashes. Methods Data on 14,742 culpable drivers (initiators) and 14,742 nonculpable drivers (non-initiators) involved in the same fatal two-vehicle crashes between 1993 and 2014 w...
Gespeichert in:
| Veröffentlicht in: | Annals of epidemiology 2017-05, Vol.27 (5), p.342-347.e1 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 347.e1 |
|---|---|
| container_issue | 5 |
| container_start_page | 342 |
| container_title | Annals of epidemiology |
| container_volume | 27 |
| creator | Li, Guohua, MD, DrPH Chihuri, Stanford, MPH Brady, Joanne E., PhD |
| description | Abstract Purpose To assess individual and joint effects of alcohol and marijuana on the initiation of fatal two-vehicle crashes. Methods Data on 14,742 culpable drivers (initiators) and 14,742 nonculpable drivers (non-initiators) involved in the same fatal two-vehicle crashes between 1993 and 2014 were obtained from the Fatality Analysis Reporting System. Multivariable conditional logistic regression models were used to assess the association of driver use of alcohol, marijuana or both with fatal crash initiation with adjustment for demographic variables. Results Initiators were significantly more likely than non-initiators to test positive for alcohol (28.3% vs. 9.6%, p |
| doi_str_mv | 10.1016/j.annepidem.2017.05.003 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1908432247</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1047279716304380</els_id><sourcerecordid>1908432247</sourcerecordid><originalsourceid>FETCH-LOGICAL-c426t-dfeacbd9e3b36b4287d8c0f0bce8ce832101eabcdb4b7598f514b4ac96b487643</originalsourceid><addsrcrecordid>eNqNkUtv1TAQRi0EoqXwFyBLNgl-JXY2SFVFS6VKoBbWlh8TXQdf-2InRf33OLqli66QLI0XZ2b0nUHoA8EdwWT4NHc6Rjh4B_uOYiI63HcYsxfolEjBWtrL_mX9Yy5aKkZxgt6UMmOMhRT0NTqhsh97weQp-n6bAjRpanSwaZdCo6Nr9jr7edVRN2uBxsdm2W3FL14vPsUNn_SiQ7P8Se097LytM2zWZQflLXo16VDg3WM9Qz8vv_y4-NrefLu6vji_aS2nw9K6CbQ1bgRm2GA4lcJJiydsLMj6GK0xQRvrDDeiH-XUE264tmOFpRg4O0Mfj3MPOf1eoSxq74uFEHSEtBZFRiw5o5SLioojanMqJcOkDtnXjA-KYLXpVLN60qk2nQr3quqsne8fl6xmD-6p75-_CpwfAahR7z1kVayHaMH5DHZRLvn_WPL52Qwbqmyrwy94gDKnNcdqUhFVqMLqbrvqdlQyMMyZxOwvrpugTg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1908432247</pqid></control><display><type>article</type><title>Role of alcohol and marijuana use in the initiation of fatal two-vehicle crashes</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Li, Guohua, MD, DrPH ; Chihuri, Stanford, MPH ; Brady, Joanne E., PhD</creator><creatorcontrib>Li, Guohua, MD, DrPH ; Chihuri, Stanford, MPH ; Brady, Joanne E., PhD</creatorcontrib><description>Abstract Purpose To assess individual and joint effects of alcohol and marijuana on the initiation of fatal two-vehicle crashes. Methods Data on 14,742 culpable drivers (initiators) and 14,742 nonculpable drivers (non-initiators) involved in the same fatal two-vehicle crashes between 1993 and 2014 were obtained from the Fatality Analysis Reporting System. Multivariable conditional logistic regression models were used to assess the association of driver use of alcohol, marijuana or both with fatal crash initiation with adjustment for demographic variables. Results Initiators were significantly more likely than non-initiators to test positive for alcohol (28.3% vs. 9.6%, p<0.0001), marijuana (10.4% vs. 6.0%, p<0.0001) and both substances (4.4% vs. 1.1%, p<0.0001). Relative to drivers testing negative for both alcohol and marijuana, the adjusted odds ratios of fatal crash initiation were 3.70 (95% confidence interval [CI]: 3.42 to 4.00) for those testing positive for alcohol and negative for marijuana, 1.48 (95% CI: 1.32 to 1.65) for those testing positive for marijuana and negative for alcohol, and 5.46 (95% CI: 4.73-6.31) for those testing positive for both alcohol and marijuana. Conclusions Alcohol and marijuana each play a significant role in fatal crash initiation. When used in combination, alcohol and marijuana appear to have a positive interaction effect on the risk of fatal crash initiation on the additive scale.</description><identifier>ISSN: 1047-2797</identifier><identifier>EISSN: 1873-2585</identifier><identifier>DOI: 10.1016/j.annepidem.2017.05.003</identifier><identifier>PMID: 28595738</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Accidents ; Accidents, Traffic - mortality ; Accidents, Traffic - statistics & numerical data ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Alcohol ; Alcohol Drinking - adverse effects ; Alcohol Drinking - epidemiology ; Automobile Driving ; Blood Alcohol Content ; Case-Control Studies ; Driving Under the Influence - statistics & numerical data ; Drug interaction ; Female ; Humans ; Internal Medicine ; Logistic Models ; Male ; Marijuana ; Marijuana Smoking - adverse effects ; Marijuana Smoking - epidemiology ; Marijuana Use - adverse effects ; Middle Aged ; Motor Vehicles ; New York - epidemiology ; Odds Ratio ; Risk Factors ; Safety ; Traffic</subject><ispartof>Annals of epidemiology, 2017-05, Vol.27 (5), p.342-347.e1</ispartof><rights>Elsevier Inc.</rights><rights>2017 Elsevier Inc.</rights><rights>Copyright © 2017 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c426t-dfeacbd9e3b36b4287d8c0f0bce8ce832101eabcdb4b7598f514b4ac96b487643</citedby><cites>FETCH-LOGICAL-c426t-dfeacbd9e3b36b4287d8c0f0bce8ce832101eabcdb4b7598f514b4ac96b487643</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.annepidem.2017.05.003$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28595738$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Guohua, MD, DrPH</creatorcontrib><creatorcontrib>Chihuri, Stanford, MPH</creatorcontrib><creatorcontrib>Brady, Joanne E., PhD</creatorcontrib><title>Role of alcohol and marijuana use in the initiation of fatal two-vehicle crashes</title><title>Annals of epidemiology</title><addtitle>Ann Epidemiol</addtitle><description>Abstract Purpose To assess individual and joint effects of alcohol and marijuana on the initiation of fatal two-vehicle crashes. Methods Data on 14,742 culpable drivers (initiators) and 14,742 nonculpable drivers (non-initiators) involved in the same fatal two-vehicle crashes between 1993 and 2014 were obtained from the Fatality Analysis Reporting System. Multivariable conditional logistic regression models were used to assess the association of driver use of alcohol, marijuana or both with fatal crash initiation with adjustment for demographic variables. Results Initiators were significantly more likely than non-initiators to test positive for alcohol (28.3% vs. 9.6%, p<0.0001), marijuana (10.4% vs. 6.0%, p<0.0001) and both substances (4.4% vs. 1.1%, p<0.0001). Relative to drivers testing negative for both alcohol and marijuana, the adjusted odds ratios of fatal crash initiation were 3.70 (95% confidence interval [CI]: 3.42 to 4.00) for those testing positive for alcohol and negative for marijuana, 1.48 (95% CI: 1.32 to 1.65) for those testing positive for marijuana and negative for alcohol, and 5.46 (95% CI: 4.73-6.31) for those testing positive for both alcohol and marijuana. Conclusions Alcohol and marijuana each play a significant role in fatal crash initiation. When used in combination, alcohol and marijuana appear to have a positive interaction effect on the risk of fatal crash initiation on the additive scale.</description><subject>Accidents</subject><subject>Accidents, Traffic - mortality</subject><subject>Accidents, Traffic - statistics & numerical data</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Alcohol</subject><subject>Alcohol Drinking - adverse effects</subject><subject>Alcohol Drinking - epidemiology</subject><subject>Automobile Driving</subject><subject>Blood Alcohol Content</subject><subject>Case-Control Studies</subject><subject>Driving Under the Influence - statistics & numerical data</subject><subject>Drug interaction</subject><subject>Female</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Marijuana</subject><subject>Marijuana Smoking - adverse effects</subject><subject>Marijuana Smoking - epidemiology</subject><subject>Marijuana Use - adverse effects</subject><subject>Middle Aged</subject><subject>Motor Vehicles</subject><subject>New York - epidemiology</subject><subject>Odds Ratio</subject><subject>Risk Factors</subject><subject>Safety</subject><subject>Traffic</subject><issn>1047-2797</issn><issn>1873-2585</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkUtv1TAQRi0EoqXwFyBLNgl-JXY2SFVFS6VKoBbWlh8TXQdf-2InRf33OLqli66QLI0XZ2b0nUHoA8EdwWT4NHc6Rjh4B_uOYiI63HcYsxfolEjBWtrL_mX9Yy5aKkZxgt6UMmOMhRT0NTqhsh97weQp-n6bAjRpanSwaZdCo6Nr9jr7edVRN2uBxsdm2W3FL14vPsUNn_SiQ7P8Se097LytM2zWZQflLXo16VDg3WM9Qz8vv_y4-NrefLu6vji_aS2nw9K6CbQ1bgRm2GA4lcJJiydsLMj6GK0xQRvrDDeiH-XUE264tmOFpRg4O0Mfj3MPOf1eoSxq74uFEHSEtBZFRiw5o5SLioojanMqJcOkDtnXjA-KYLXpVLN60qk2nQr3quqsne8fl6xmD-6p75-_CpwfAahR7z1kVayHaMH5DHZRLvn_WPL52Qwbqmyrwy94gDKnNcdqUhFVqMLqbrvqdlQyMMyZxOwvrpugTg</recordid><startdate>20170501</startdate><enddate>20170501</enddate><creator>Li, Guohua, MD, DrPH</creator><creator>Chihuri, Stanford, MPH</creator><creator>Brady, Joanne E., PhD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170501</creationdate><title>Role of alcohol and marijuana use in the initiation of fatal two-vehicle crashes</title><author>Li, Guohua, MD, DrPH ; Chihuri, Stanford, MPH ; Brady, Joanne E., PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c426t-dfeacbd9e3b36b4287d8c0f0bce8ce832101eabcdb4b7598f514b4ac96b487643</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Accidents</topic><topic>Accidents, Traffic - mortality</topic><topic>Accidents, Traffic - statistics & numerical data</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Alcohol</topic><topic>Alcohol Drinking - adverse effects</topic><topic>Alcohol Drinking - epidemiology</topic><topic>Automobile Driving</topic><topic>Blood Alcohol Content</topic><topic>Case-Control Studies</topic><topic>Driving Under the Influence - statistics & numerical data</topic><topic>Drug interaction</topic><topic>Female</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Marijuana</topic><topic>Marijuana Smoking - adverse effects</topic><topic>Marijuana Smoking - epidemiology</topic><topic>Marijuana Use - adverse effects</topic><topic>Middle Aged</topic><topic>Motor Vehicles</topic><topic>New York - epidemiology</topic><topic>Odds Ratio</topic><topic>Risk Factors</topic><topic>Safety</topic><topic>Traffic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Guohua, MD, DrPH</creatorcontrib><creatorcontrib>Chihuri, Stanford, MPH</creatorcontrib><creatorcontrib>Brady, Joanne E., PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Guohua, MD, DrPH</au><au>Chihuri, Stanford, MPH</au><au>Brady, Joanne E., PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of alcohol and marijuana use in the initiation of fatal two-vehicle crashes</atitle><jtitle>Annals of epidemiology</jtitle><addtitle>Ann Epidemiol</addtitle><date>2017-05-01</date><risdate>2017</risdate><volume>27</volume><issue>5</issue><spage>342</spage><epage>347.e1</epage><pages>342-347.e1</pages><issn>1047-2797</issn><eissn>1873-2585</eissn><abstract>Abstract Purpose To assess individual and joint effects of alcohol and marijuana on the initiation of fatal two-vehicle crashes. Methods Data on 14,742 culpable drivers (initiators) and 14,742 nonculpable drivers (non-initiators) involved in the same fatal two-vehicle crashes between 1993 and 2014 were obtained from the Fatality Analysis Reporting System. Multivariable conditional logistic regression models were used to assess the association of driver use of alcohol, marijuana or both with fatal crash initiation with adjustment for demographic variables. Results Initiators were significantly more likely than non-initiators to test positive for alcohol (28.3% vs. 9.6%, p<0.0001), marijuana (10.4% vs. 6.0%, p<0.0001) and both substances (4.4% vs. 1.1%, p<0.0001). Relative to drivers testing negative for both alcohol and marijuana, the adjusted odds ratios of fatal crash initiation were 3.70 (95% confidence interval [CI]: 3.42 to 4.00) for those testing positive for alcohol and negative for marijuana, 1.48 (95% CI: 1.32 to 1.65) for those testing positive for marijuana and negative for alcohol, and 5.46 (95% CI: 4.73-6.31) for those testing positive for both alcohol and marijuana. Conclusions Alcohol and marijuana each play a significant role in fatal crash initiation. When used in combination, alcohol and marijuana appear to have a positive interaction effect on the risk of fatal crash initiation on the additive scale.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>28595738</pmid><doi>10.1016/j.annepidem.2017.05.003</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1047-2797 |
| ispartof | Annals of epidemiology, 2017-05, Vol.27 (5), p.342-347.e1 |
| issn | 1047-2797 1873-2585 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1908432247 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Accidents Accidents, Traffic - mortality Accidents, Traffic - statistics & numerical data Adolescent Adult Aged Aged, 80 and over Alcohol Alcohol Drinking - adverse effects Alcohol Drinking - epidemiology Automobile Driving Blood Alcohol Content Case-Control Studies Driving Under the Influence - statistics & numerical data Drug interaction Female Humans Internal Medicine Logistic Models Male Marijuana Marijuana Smoking - adverse effects Marijuana Smoking - epidemiology Marijuana Use - adverse effects Middle Aged Motor Vehicles New York - epidemiology Odds Ratio Risk Factors Safety Traffic |
| title | Role of alcohol and marijuana use in the initiation of fatal two-vehicle crashes |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T14%3A26%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Role%20of%20alcohol%20and%20marijuana%20use%20in%20the%20initiation%20of%20fatal%20two-vehicle%20crashes&rft.jtitle=Annals%20of%20epidemiology&rft.au=Li,%20Guohua,%20MD,%20DrPH&rft.date=2017-05-01&rft.volume=27&rft.issue=5&rft.spage=342&rft.epage=347.e1&rft.pages=342-347.e1&rft.issn=1047-2797&rft.eissn=1873-2585&rft_id=info:doi/10.1016/j.annepidem.2017.05.003&rft_dat=%3Cproquest_cross%3E1908432247%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1908432247&rft_id=info:pmid/28595738&rft_els_id=S1047279716304380&rfr_iscdi=true |