Effects of cyclodextrins on the chemical stability of drugs

[Display omitted] Cyclodextrins (CDs) are enabling pharmaceutical excipients that can enhance both solubility and stability of wide variety of drugs in aqueous solutions through formation of drug/CD inclusion complexes where apolar moieties of the drug molecules are located inside the CD cavity. In...

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Veröffentlicht in:	International journal of pharmaceutics 2017-10, Vol.531 (2), p.532-542
Hauptverfasser:	Popielec, Agnieszka, Loftsson, Thorsteinn
Format:	Artikel
Sprache:	eng
Schlagworte:	Aqueous solution Catalysis Chemistry, Pharmaceutical Complexation Cyclodextrins - chemistry Drug degradation Drug Stability Excipients - chemistry Solubility Stabilization
Online-Zugang:	Volltext
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