Preparation, characterization, and cytotoxicity studies of niclosamide loaded mesoporous drug delivery systems

[Display omitted] Recent reports on the anticancer potential of niclosamide have opened new avenues for anticancer treatment. Niclosamide belongs to the BCS class II, which is indicative of poor solubility and dissolution rate limited absorption. The aim of this study was to improve the dissolution...

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Veröffentlicht in:	International journal of pharmaceutics 2017-08, Vol.528 (1-2), p.202-214
Hauptverfasser:	Pardhi, Vishwas, Chavan, Rahul B, Thipparaboina, Rajesh, Thatikonda, Sowjanya, Naidu, VGM, Shastri, Nalini R
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cell Line, Tumor Dissolution Drug Carriers - chemistry Humans Niclosamide - administration & dosage Porosity Repurposed Silica Silicon Dioxide - chemistry Solubility
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