The use of mechano growth factor to prevent cartilage degeneration in knee osteoarthritis

Previous studies have attached more importance to growth factors in treating cartilage degeneration and osteoarthritis (OA). Here, the capability of mechano growth factor‐C24E (MGF) to prevent osteoarthritic cartilage degeneration was evaluated in vitro and in vivo. Using in vitro cultured human OA...

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Veröffentlicht in:	Journal of tissue engineering and regenerative medicine 2018-03, Vol.12 (3), p.738-749
Hauptverfasser:	Song, Yang, Xu, Kang, Yu, Can, Dong, Lili, Chen, Peixing, Lv, Yonggang, Chiang, Martin Y.M., Li, Linhao, Liu, Wanqian, Yang, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Arthritis Biocompatibility Biomedical materials Cartilage cartilage degeneration Cartilage diseases Cell migration Cell proliferation Chondrocytes Degeneration Endoplasmic reticulum Growth factors Hypoxia Kinases Knee mechano growth factor Osteoarthritis PERK Protein folding Protein kinase Proteins Regenerative medicine Ribonucleic acid RNA siRNA Smad protein Tissue engineering Transforming growth factor Transforming growth factor-b unfolded protein response Western blotting
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