Tomato (Lycopersicon esculentum) or lycopene supplementation attenuates ventricular remodeling after myocardial infarction through different mechanistic pathways

The objective of this study was to evaluate the influence of tomato or lycopene supplementation on cardiac remodeling after myocardial infarction (MI). Male Wistar rats were assigned to four groups: the sham group (animals that underwent simulated surgery) that received a standard chow (S; n=18), th...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2017-08, Vol.46, p.117-124
Hauptverfasser:	Pereira, Bruna L.B., Reis, Patrícia P., Severino, Fábio E., Felix, Tainara F., Braz, Mariana G., Nogueira, Flávia R., Silva, Renata A.C., Cardoso, Ana C., Lourenço, Maria A.M., Figueiredo, Amanda M., Chiuso-Minicucci, Fernanda, Azevedo, Paula S., Polegato, Bertha F., Okoshi, Katashi, Fernandes, Ana A.H., Paiva, Sergio A.R., Zornoff, Leonardo A.M., Minicucci, Marcos F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carotenoids - pharmacology Dietary Supplements Electrocardiography Epigenetics Gene Expression Regulation Lycopene Lycopersicon esculentum - chemistry Male microRNA MicroRNAs Myocardial infarction Myocardial Infarction - diet therapy Myocardial Infarction - metabolism Myocardial Infarction - physiopathology NF-E2-Related Factor 2 - metabolism Nutrition Rats, Wistar Remodeling Tumor Necrosis Factor-alpha - metabolism Ventricular Remodeling - drug effects Ventricular Remodeling - genetics
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