Antibacterial Prophylaxis for Surgical Site Infection in the Elderly: Practical Application

Surgical site infections are among the most common healthcare-associated infections and are linked with increased length of hospitalization, re-admission, mortality and significant financial burden. Risk factors for the occurrence of surgical site infections include variables related to the surgical...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Drugs & aging 2017-07, Vol.34 (7), p.489-498
Hauptverfasser: Cataldo, Maria Adriana, Granata, Guido, Petrosillo, Nicola
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 498
container_issue 7
container_start_page 489
container_title Drugs & aging
container_volume 34
creator Cataldo, Maria Adriana
Granata, Guido
Petrosillo, Nicola
description Surgical site infections are among the most common healthcare-associated infections and are linked with increased length of hospitalization, re-admission, mortality and significant financial burden. Risk factors for the occurrence of surgical site infections include variables related to the surgical procedure as well as host factors. Increasing age is associated with the occurrence of surgical site infections. The aim of this review is to give an update on the antibiotic prophylaxis for surgical site infection in elderly people. We focused on specific issues and practical applications, such as the importance of targeting the antimicrobial agent to the susceptibility pattern of colonizing flora in selected cases and the need for dosage modifications.
doi_str_mv 10.1007/s40266-017-0471-9
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1907006949</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1907006949</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-3ac746ed0c578b3f0772b40754a1aa800edb1873ee9201194a5ab8acb10c0c83</originalsourceid><addsrcrecordid>eNp1kEFLwzAUx4MoTqcfwIsUvHipvqRZ03gbY-pgoLAdBA8hTdMto2tr0oL79qbrFBG8JA_e7_1e8kfoCsMdBmD3jgKJ4xAwC4EyHPIjdIYx4yHmMT_e1xASwt8G6Ny5DQDEhOBTNCDJKOE0js_Q-7hsTCpVo62RRfBqq3q9K-SncUFe2WDR2pVRvrEwjQ5mZa5VY6oyMGXQrHUwLTJti92Dn_OKPTiu68IXHXWBTnJZOH15uIdo-ThdTp7D-cvTbDKehypipAkjqRiNdQZqxJI0yoExklJgIyqxlAmAzlKcsEhrTgBjTuVIpolUKQYFKomG6LbX1rb6aLVrxNY4pYtClrpqncAcmP85p9yjN3_QTdXa0j_OUyyKIujOIcI9pWzlnNW5qK3ZSrsTGEQXvOiDFz540QUvOvP1wdymW539THwn7QHSA863ypW2v1b_a_0CbIWNjQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1973330973</pqid></control><display><type>article</type><title>Antibacterial Prophylaxis for Surgical Site Infection in the Elderly: Practical Application</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Cataldo, Maria Adriana ; Granata, Guido ; Petrosillo, Nicola</creator><creatorcontrib>Cataldo, Maria Adriana ; Granata, Guido ; Petrosillo, Nicola</creatorcontrib><description>Surgical site infections are among the most common healthcare-associated infections and are linked with increased length of hospitalization, re-admission, mortality and significant financial burden. Risk factors for the occurrence of surgical site infections include variables related to the surgical procedure as well as host factors. Increasing age is associated with the occurrence of surgical site infections. The aim of this review is to give an update on the antibiotic prophylaxis for surgical site infection in elderly people. We focused on specific issues and practical applications, such as the importance of targeting the antimicrobial agent to the susceptibility pattern of colonizing flora in selected cases and the need for dosage modifications.</description><identifier>ISSN: 1170-229X</identifier><identifier>EISSN: 1179-1969</identifier><identifier>DOI: 10.1007/s40266-017-0471-9</identifier><identifier>PMID: 28589466</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Aged ; Anti-Bacterial Agents - administration &amp; dosage ; Anti-Bacterial Agents - pharmacokinetics ; Anti-Bacterial Agents - therapeutic use ; Antibiotic Prophylaxis - methods ; Antibiotics ; Antimicrobial agents ; Diabetes ; Disease control ; Disease prevention ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Drug dosages ; Geriatrics/Gerontology ; Humans ; Infections ; Internal Medicine ; Malnutrition ; Medicine ; Medicine &amp; Public Health ; Mortality ; Older people ; Pharmacology/Toxicology ; Pharmacotherapy ; Population ; Prostate ; Risk Factors ; Surgery ; Surgical outcomes ; Surgical site infections ; Surgical Wound Infection - microbiology ; Surgical Wound Infection - prevention &amp; control ; Therapy in Practice</subject><ispartof>Drugs &amp; aging, 2017-07, Vol.34 (7), p.489-498</ispartof><rights>Springer International Publishing Switzerland 2017</rights><rights>Copyright Springer Science &amp; Business Media Jul 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-3ac746ed0c578b3f0772b40754a1aa800edb1873ee9201194a5ab8acb10c0c83</citedby><cites>FETCH-LOGICAL-c372t-3ac746ed0c578b3f0772b40754a1aa800edb1873ee9201194a5ab8acb10c0c83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s40266-017-0471-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s40266-017-0471-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28589466$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cataldo, Maria Adriana</creatorcontrib><creatorcontrib>Granata, Guido</creatorcontrib><creatorcontrib>Petrosillo, Nicola</creatorcontrib><title>Antibacterial Prophylaxis for Surgical Site Infection in the Elderly: Practical Application</title><title>Drugs &amp; aging</title><addtitle>Drugs Aging</addtitle><addtitle>Drugs Aging</addtitle><description>Surgical site infections are among the most common healthcare-associated infections and are linked with increased length of hospitalization, re-admission, mortality and significant financial burden. Risk factors for the occurrence of surgical site infections include variables related to the surgical procedure as well as host factors. Increasing age is associated with the occurrence of surgical site infections. The aim of this review is to give an update on the antibiotic prophylaxis for surgical site infection in elderly people. We focused on specific issues and practical applications, such as the importance of targeting the antimicrobial agent to the susceptibility pattern of colonizing flora in selected cases and the need for dosage modifications.</description><subject>Aged</subject><subject>Anti-Bacterial Agents - administration &amp; dosage</subject><subject>Anti-Bacterial Agents - pharmacokinetics</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotic Prophylaxis - methods</subject><subject>Antibiotics</subject><subject>Antimicrobial agents</subject><subject>Diabetes</subject><subject>Disease control</subject><subject>Disease prevention</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Administration Schedule</subject><subject>Drug dosages</subject><subject>Geriatrics/Gerontology</subject><subject>Humans</subject><subject>Infections</subject><subject>Internal Medicine</subject><subject>Malnutrition</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Mortality</subject><subject>Older people</subject><subject>Pharmacology/Toxicology</subject><subject>Pharmacotherapy</subject><subject>Population</subject><subject>Prostate</subject><subject>Risk Factors</subject><subject>Surgery</subject><subject>Surgical outcomes</subject><subject>Surgical site infections</subject><subject>Surgical Wound Infection - microbiology</subject><subject>Surgical Wound Infection - prevention &amp; control</subject><subject>Therapy in Practice</subject><issn>1170-229X</issn><issn>1179-1969</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kEFLwzAUx4MoTqcfwIsUvHipvqRZ03gbY-pgoLAdBA8hTdMto2tr0oL79qbrFBG8JA_e7_1e8kfoCsMdBmD3jgKJ4xAwC4EyHPIjdIYx4yHmMT_e1xASwt8G6Ny5DQDEhOBTNCDJKOE0js_Q-7hsTCpVo62RRfBqq3q9K-SncUFe2WDR2pVRvrEwjQ5mZa5VY6oyMGXQrHUwLTJti92Dn_OKPTiu68IXHXWBTnJZOH15uIdo-ThdTp7D-cvTbDKehypipAkjqRiNdQZqxJI0yoExklJgIyqxlAmAzlKcsEhrTgBjTuVIpolUKQYFKomG6LbX1rb6aLVrxNY4pYtClrpqncAcmP85p9yjN3_QTdXa0j_OUyyKIujOIcI9pWzlnNW5qK3ZSrsTGEQXvOiDFz540QUvOvP1wdymW539THwn7QHSA863ypW2v1b_a_0CbIWNjQ</recordid><startdate>20170701</startdate><enddate>20170701</enddate><creator>Cataldo, Maria Adriana</creator><creator>Granata, Guido</creator><creator>Petrosillo, Nicola</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>4T-</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20170701</creationdate><title>Antibacterial Prophylaxis for Surgical Site Infection in the Elderly: Practical Application</title><author>Cataldo, Maria Adriana ; Granata, Guido ; Petrosillo, Nicola</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-3ac746ed0c578b3f0772b40754a1aa800edb1873ee9201194a5ab8acb10c0c83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Aged</topic><topic>Anti-Bacterial Agents - administration &amp; dosage</topic><topic>Anti-Bacterial Agents - pharmacokinetics</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antibiotic Prophylaxis - methods</topic><topic>Antibiotics</topic><topic>Antimicrobial agents</topic><topic>Diabetes</topic><topic>Disease control</topic><topic>Disease prevention</topic><topic>Dose-Response Relationship, Drug</topic><topic>Drug Administration Schedule</topic><topic>Drug dosages</topic><topic>Geriatrics/Gerontology</topic><topic>Humans</topic><topic>Infections</topic><topic>Internal Medicine</topic><topic>Malnutrition</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Mortality</topic><topic>Older people</topic><topic>Pharmacology/Toxicology</topic><topic>Pharmacotherapy</topic><topic>Population</topic><topic>Prostate</topic><topic>Risk Factors</topic><topic>Surgery</topic><topic>Surgical outcomes</topic><topic>Surgical site infections</topic><topic>Surgical Wound Infection - microbiology</topic><topic>Surgical Wound Infection - prevention &amp; control</topic><topic>Therapy in Practice</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cataldo, Maria Adriana</creatorcontrib><creatorcontrib>Granata, Guido</creatorcontrib><creatorcontrib>Petrosillo, Nicola</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Drugs &amp; aging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cataldo, Maria Adriana</au><au>Granata, Guido</au><au>Petrosillo, Nicola</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antibacterial Prophylaxis for Surgical Site Infection in the Elderly: Practical Application</atitle><jtitle>Drugs &amp; aging</jtitle><stitle>Drugs Aging</stitle><addtitle>Drugs Aging</addtitle><date>2017-07-01</date><risdate>2017</risdate><volume>34</volume><issue>7</issue><spage>489</spage><epage>498</epage><pages>489-498</pages><issn>1170-229X</issn><eissn>1179-1969</eissn><abstract>Surgical site infections are among the most common healthcare-associated infections and are linked with increased length of hospitalization, re-admission, mortality and significant financial burden. Risk factors for the occurrence of surgical site infections include variables related to the surgical procedure as well as host factors. Increasing age is associated with the occurrence of surgical site infections. The aim of this review is to give an update on the antibiotic prophylaxis for surgical site infection in elderly people. We focused on specific issues and practical applications, such as the importance of targeting the antimicrobial agent to the susceptibility pattern of colonizing flora in selected cases and the need for dosage modifications.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>28589466</pmid><doi>10.1007/s40266-017-0471-9</doi><tpages>10</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1170-229X
ispartof Drugs & aging, 2017-07, Vol.34 (7), p.489-498
issn 1170-229X
1179-1969
language eng
recordid cdi_proquest_miscellaneous_1907006949
source MEDLINE; SpringerLink Journals - AutoHoldings
subjects Aged
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - pharmacokinetics
Anti-Bacterial Agents - therapeutic use
Antibiotic Prophylaxis - methods
Antibiotics
Antimicrobial agents
Diabetes
Disease control
Disease prevention
Dose-Response Relationship, Drug
Drug Administration Schedule
Drug dosages
Geriatrics/Gerontology
Humans
Infections
Internal Medicine
Malnutrition
Medicine
Medicine & Public Health
Mortality
Older people
Pharmacology/Toxicology
Pharmacotherapy
Population
Prostate
Risk Factors
Surgery
Surgical outcomes
Surgical site infections
Surgical Wound Infection - microbiology
Surgical Wound Infection - prevention & control
Therapy in Practice
title Antibacterial Prophylaxis for Surgical Site Infection in the Elderly: Practical Application
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T10%3A44%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Antibacterial%20Prophylaxis%20for%20Surgical%20Site%20Infection%20in%20the%20Elderly:%20Practical%20Application&rft.jtitle=Drugs%20&%20aging&rft.au=Cataldo,%20Maria%20Adriana&rft.date=2017-07-01&rft.volume=34&rft.issue=7&rft.spage=489&rft.epage=498&rft.pages=489-498&rft.issn=1170-229X&rft.eissn=1179-1969&rft_id=info:doi/10.1007/s40266-017-0471-9&rft_dat=%3Cproquest_cross%3E1907006949%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1973330973&rft_id=info:pmid/28589466&rfr_iscdi=true