Diagnostic accuracy of increased urinary cortisol/cortisone ratio to differentiate ACTH‐dependent Cushing's syndrome

Summary Background and aim Differential diagnosis between Cushing's Disease (CD) and Ectopic ACTH Syndrome (EAS) may be a pitfall for endocrinologists. The increasing use in clinical practice of chromatography and mass spectrometry improves the measurement of urinary free cortisol (UFF) and cor...

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Veröffentlicht in:	Clinical endocrinology (Oxford) 2017-11, Vol.87 (5), p.500-507
Hauptverfasser:	Ceccato, Filippo, Trementino, Laura, Barbot, Mattia, Antonelli, Giorgia, Plebani, Mario, Denaro, Luca, Regazzo, Daniela, Rea, Federico, Frigo, Anna Chiara, Concettoni, Carolina, Boscaro, Marco, Arnaldi, Giorgio, Scaroni, Carla
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy ACTH Syndrome, Ectopic - diagnosis Adrenocorticotropic hormone Adult Aged Chromatography Chromatography, Liquid Cortisol cortisone Cortisone - urine Cushing syndrome Cushing's Disease Dexamethasone Diagnosis, Differential Differential diagnosis Ectopic ACTH Syndrome Female High-performance liquid chromatography Hormones Humans Hydrocortisone - urine liquid chromatography‐tandem mass spectrometry Male Mass spectrometry Mass spectroscopy Medical diagnosis Middle Aged Nervous system diseases Pituitary Pituitary ACTH Hypersecretion - diagnosis Retrospective Studies Scientific imaging Secretion Sensitivity and Specificity Tandem Mass Spectrometry urinary free cortisol
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