Diphytanoyl lipids as model systems for studying membrane-active peptides

The branched chains in diphytanoyl lipids provide membranes with unique properties, such as high chemical/physical stability, low water permeability, and no gel-to-fluid phase transition at ambient temperature. Synthetic diphytanoyl phospholipids are often used as model membranes for electrophysiolo...

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Veröffentlicht in:	Biochimica et biophysica acta. Biomembranes 2017-10, Vol.1859 (10), p.1828-1837
Hauptverfasser:	Kara, Sezgin, Afonin, Sergii, Babii, Oleg, Tkachenko, Anton N., Komarov, Igor V., Ulrich, Anne S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimicrobial peptide PGLa Cell Membrane - chemistry Circular Dichroism Diphytanoyl phospholipids Lipid Bilayers - chemistry Lipids - chemistry Magnetic Resonance Spectroscopy - methods Membrane-active peptides Models, Biological Oriented circular dichroism Peptide-lipid interactions Peptides - chemistry Phospholipids - chemistry Protein Conformation, alpha-Helical Solid-state 31P NMR and 19F NMR spectroscopy Temperature
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