Lignans from the Roots of Taxus wallichiana and Their α‑Glucosidase Inhibitory Activities

From an EtOAc-soluble extract of the roots of Taxus wallichiana, six new (1–6) and 11 known lignans were isolated. The structures of the new compounds were elucidated based on interpretation of spectroscopic data. (+)-7′-epi-Tsugacetal (1) is a rare aryltetralin-type lignan having a cis-orientation...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2017-06, Vol.80 (6), p.1876-1882
Hauptverfasser:	Dang, Phu H, Nguyen, Hai X, Nguyen, Hanh H. T, Vo, Thai D, Le, Tho H, Phan, Trong H. N, Nguyen, Mai T. T, Nguyen, Nhan T
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Glucosidases - drug effects Dose-Response Relationship, Drug Glycoside Hydrolase Inhibitors - chemistry Glycoside Hydrolase Inhibitors - isolation & purification Glycoside Hydrolase Inhibitors - pharmacology Inhibitory Concentration 50 Lignans - chemistry Lignans - isolation & purification Lignans - pharmacology Molecular Structure Plant Roots - chemistry Taxus - chemistry Vietnam
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