The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology

Certain transcription factors have vital roles in lineage development, including specification of cell types and control of differentiation. Microphthalmia-associated transcription factor (MITF) is a key transcription factor for melanocyte development and differentiation. MITF regulates expression o...

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Veröffentlicht in:	Laboratory investigation 2017-06, Vol.97 (6), p.649-656
Hauptverfasser:	Kawakami, Akinori, Fisher, David E
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1813/1634 692/420/755 Animals Humans Laboratory Medicine Medicine Medicine & Public Health Melanocytes - cytology Melanocytes - metabolism Melanocytes - physiology Melanoma - metabolism Melanoma - physiopathology Mice Microphthalmia-Associated Transcription Factor - metabolism Microphthalmia-Associated Transcription Factor - physiology pathobiology-in-focus Pathology Signal Transduction - physiology
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