SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells

Bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) is a transforming growth factor β (TGF-β) type I receptor antagonist that negatively regulates TGF-β and bone morphogenetic protein (BMP) signaling. BAMBI has been shown to be regulated by TGF-β signaling; however, whether BAMBI...

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Veröffentlicht in:	Cellular signalling 2017-09, Vol.37, p.52-61
Hauptverfasser:	Bai, Long, Chang, Hsun-Ming, Cheng, Jung-Chien, Klausen, Christian, Chu, Guiyan, Leung, Peter C.K., Yang, Gongshe
Format:	Artikel
Sprache:	eng
Schlagworte:	BAMBI BMP2 Bone Morphogenetic Protein 2 - metabolism Cell Line Female Human granulosa cells Humans Luteal Cells - metabolism Membrane Proteins - genetics RNA, Messenger - genetics Signal Transduction Smad Proteins - metabolism SMAD1 SMAD5 Up-Regulation
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