Features of Blood Supply to Axillary Lymph Nodes in Breast Cancer Patients
Numerical density of vessels in axillary lymph node structures in breast cancer patients was studied by light microscopy with antibodies to CD34. The correlation between the stage of breast cancer and vascularization of lymph nodes was analyzed. The development of breast cancer was followed by rapid...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 2017-05, Vol.163 (1), p.82-86 |
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| creator | Maiborodin, I. V. Kozyakov, A. E. Babayants, E. V. Krasil’nikov, S. E. |
| description | Numerical density of vessels in axillary lymph node structures in breast cancer patients was studied by light microscopy with antibodies to CD34. The correlation between the stage of breast cancer and vascularization of lymph nodes was analyzed. The development of breast cancer was followed by rapid and significant increase in the number of blood vessel in axillary lymph nodes in general and in all their specific areas, especially in the paracortex and medullary substance. Strong or very strong positive correlation between the stage of tumor process and parameters of vascularization was observed in various areas of the axillary lymph nodes. No significant differences in node vascularization were observed between women without breast cancer and women with stage I breast cancer; the differences were found only starting from stage II. Considerable vascularization of lymph nodes can be a symptom of malignant tumor growth in the area of lymph collection. The duration of the tumor process and the size of the tumor can be indirectly evaluated by the increase in vessel number in lymph nodes. |
| doi_str_mv | 10.1007/s10517-017-3743-9 |
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No significant differences in node vascularization were observed between women without breast cancer and women with stage I breast cancer; the differences were found only starting from stage II. Considerable vascularization of lymph nodes can be a symptom of malignant tumor growth in the area of lymph collection. 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All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-715f43856d895036ed42da773284dae7e030ae4a7ed39294555270059b7b71d53</citedby><cites>FETCH-LOGICAL-c470t-715f43856d895036ed42da773284dae7e030ae4a7ed39294555270059b7b71d53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10517-017-3743-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10517-017-3743-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28580489$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Maiborodin, I. V.</creatorcontrib><creatorcontrib>Kozyakov, A. E.</creatorcontrib><creatorcontrib>Babayants, E. V.</creatorcontrib><creatorcontrib>Krasil’nikov, S. E.</creatorcontrib><title>Features of Blood Supply to Axillary Lymph Nodes in Breast Cancer Patients</title><title>Bulletin of experimental biology and medicine</title><addtitle>Bull Exp Biol Med</addtitle><addtitle>Bull Exp Biol Med</addtitle><description>Numerical density of vessels in axillary lymph node structures in breast cancer patients was studied by light microscopy with antibodies to CD34. The correlation between the stage of breast cancer and vascularization of lymph nodes was analyzed. The development of breast cancer was followed by rapid and significant increase in the number of blood vessel in axillary lymph nodes in general and in all their specific areas, especially in the paracortex and medullary substance. Strong or very strong positive correlation between the stage of tumor process and parameters of vascularization was observed in various areas of the axillary lymph nodes. No significant differences in node vascularization were observed between women without breast cancer and women with stage I breast cancer; the differences were found only starting from stage II. Considerable vascularization of lymph nodes can be a symptom of malignant tumor growth in the area of lymph collection. The duration of the tumor process and the size of the tumor can be indirectly evaluated by the increase in vessel number in lymph nodes.</description><subject>Analysis</subject><subject>Antibodies</subject><subject>Axilla</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Biopsy</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - blood supply</subject><subject>Breast Neoplasms - pathology</subject><subject>Cancer patients</subject><subject>Care and treatment</subject><subject>CD34 antigen</subject><subject>Cell Biology</subject><subject>Development and progression</subject><subject>Female</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Laboratory Medicine</subject><subject>Lymph nodes</subject><subject>Lymph Nodes - blood supply</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic system</subject><subject>Mastectomy</subject><subject>Neovascularization, Physiologic - physiology</subject><subject>Pathology</subject><subject>Vascularization</subject><issn>0007-4888</issn><issn>1573-8221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kV9rFDEUxYNY7Fr9AL5IQCi-TM3fSfK4Xay1LFVQn0N2cqc7ZWYyJhlwv71ZttVWKiGEJL9zuPcehN5QckYJUR8SJZKqipTNleCVeYYWVCpeacboc7QgBaqE1voYvUzpdn8lNX2BjpmWmghtFujqAlyeIyQcWnzeh-Dxt3ma-h3OAS9_dX3v4g6vd8O0xdfBF64b8XkElzJeubGBiL-63MGY0yt01Lo-weu78wT9uPj4fXVZrb98-rxarqtGKJIrRWUruJa110YSXoMXzDulONPCO1BAOHEgnALPDTNCSskUIdJs1EZRL_kJen_wnWL4OUPKduhSA6XSEcKcLDWlSa6MJgV99w96G-Y4luoKVWujFa_ZX-rG9WC7sQ05umZvapfClFFxrmmhzp6gyvIwdE0Yoe3K-yPB6QPBFlyftyn0c-7CmB6D9AA2MaQUobVT7IYyd0uJ3QdtD0HbErTdB21N0by962zeDOD_KO6TLQA7AKl8jTcQH7T-X9ffsuCtwQ</recordid><startdate>20170501</startdate><enddate>20170501</enddate><creator>Maiborodin, I. 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V. ; Kozyakov, A. E. ; Babayants, E. V. ; Krasil’nikov, S. E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-715f43856d895036ed42da773284dae7e030ae4a7ed39294555270059b7b71d53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Analysis</topic><topic>Antibodies</topic><topic>Axilla</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Biopsy</topic><topic>Breast cancer</topic><topic>Breast Neoplasms - blood supply</topic><topic>Breast Neoplasms - pathology</topic><topic>Cancer patients</topic><topic>Care and treatment</topic><topic>CD34 antigen</topic><topic>Cell Biology</topic><topic>Development and progression</topic><topic>Female</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Laboratory Medicine</topic><topic>Lymph nodes</topic><topic>Lymph Nodes - blood supply</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphatic system</topic><topic>Mastectomy</topic><topic>Neovascularization, Physiologic - physiology</topic><topic>Pathology</topic><topic>Vascularization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Maiborodin, I. 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The development of breast cancer was followed by rapid and significant increase in the number of blood vessel in axillary lymph nodes in general and in all their specific areas, especially in the paracortex and medullary substance. Strong or very strong positive correlation between the stage of tumor process and parameters of vascularization was observed in various areas of the axillary lymph nodes. No significant differences in node vascularization were observed between women without breast cancer and women with stage I breast cancer; the differences were found only starting from stage II. Considerable vascularization of lymph nodes can be a symptom of malignant tumor growth in the area of lymph collection. 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| subjects | Analysis Antibodies Axilla Biomedical and Life Sciences Biomedicine Biopsy Breast cancer Breast Neoplasms - blood supply Breast Neoplasms - pathology Cancer patients Care and treatment CD34 antigen Cell Biology Development and progression Female Humans Internal Medicine Laboratory Medicine Lymph nodes Lymph Nodes - blood supply Lymph Nodes - pathology Lymphatic system Mastectomy Neovascularization, Physiologic - physiology Pathology Vascularization |
| title | Features of Blood Supply to Axillary Lymph Nodes in Breast Cancer Patients |
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