Ratiometric Fluorescent Probes for the Detection of Reactive Oxygen Species
Reactive oxygen species (ROS) are endogenously produced oxidants with various functions ranging from host defense to signaling. These transient species can cause severe damage to the body when their production is dysregulated or when environmental factors elevate their concentrations. To study their...
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| Veröffentlicht in: | Chemistry : a European journal 2017-10, Vol.23 (55), p.13549-13573 |
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| container_end_page | 13573 |
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| container_issue | 55 |
| container_start_page | 13549 |
| container_title | Chemistry : a European journal |
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| creator | Andina, Diana Leroux, Jean‐Christophe Luciani, Paola |
| description | Reactive oxygen species (ROS) are endogenously produced oxidants with various functions ranging from host defense to signaling. These transient species can cause severe damage to the body when their production is dysregulated or when environmental factors elevate their concentrations. To study their effects and prevent oxidative harm, tools capable of monitoring ROS in cells and tissue in a sensitive and selective fashion are required. In this Review, a summary of existing ratiometric probes is provided, together with a critical discussion of selected examples.
Bright ideas: Reactive oxygen species (ROS) are endogenously produced oxidants with various functions ranging from host defense to signaling. To study their effects and prevent oxidative harm, tools capable of monitoring ROS in cells and tissue in a sensitive and selective fashion are required. In this Review, a summary of existing ratiometric probes is provided, together with a critical discussion of selected examples. |
| doi_str_mv | 10.1002/chem.201702458 |
| format | Article |
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Bright ideas: Reactive oxygen species (ROS) are endogenously produced oxidants with various functions ranging from host defense to signaling. To study their effects and prevent oxidative harm, tools capable of monitoring ROS in cells and tissue in a sensitive and selective fashion are required. In this Review, a summary of existing ratiometric probes is provided, together with a critical discussion of selected examples.</description><identifier>ISSN: 0947-6539</identifier><identifier>EISSN: 1521-3765</identifier><identifier>DOI: 10.1002/chem.201702458</identifier><identifier>PMID: 28561437</identifier><language>eng</language><publisher>Germany: Wiley Subscription Services, Inc</publisher><subject>Chemistry ; Environmental factors ; Environmental monitoring ; Fluorescence ; Fluorescent indicators ; fluorescent probes ; Oxidants ; Oxidizing agents ; Probes ; ratiometric ; Reactive oxygen species ; sensors ; Species</subject><ispartof>Chemistry : a European journal, 2017-10, Vol.23 (55), p.13549-13573</ispartof><rights>2017 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><rights>2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.</rights><rights>2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4768-4e3e858528ff4b7a2234de196c593f5f3063b92a876f547a558e103b6eba24f73</citedby><cites>FETCH-LOGICAL-c4768-4e3e858528ff4b7a2234de196c593f5f3063b92a876f547a558e103b6eba24f73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fchem.201702458$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fchem.201702458$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,778,782,1414,27911,27912,45561,45562</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28561437$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Andina, Diana</creatorcontrib><creatorcontrib>Leroux, Jean‐Christophe</creatorcontrib><creatorcontrib>Luciani, Paola</creatorcontrib><title>Ratiometric Fluorescent Probes for the Detection of Reactive Oxygen Species</title><title>Chemistry : a European journal</title><addtitle>Chemistry</addtitle><description>Reactive oxygen species (ROS) are endogenously produced oxidants with various functions ranging from host defense to signaling. These transient species can cause severe damage to the body when their production is dysregulated or when environmental factors elevate their concentrations. To study their effects and prevent oxidative harm, tools capable of monitoring ROS in cells and tissue in a sensitive and selective fashion are required. In this Review, a summary of existing ratiometric probes is provided, together with a critical discussion of selected examples.
Bright ideas: Reactive oxygen species (ROS) are endogenously produced oxidants with various functions ranging from host defense to signaling. To study their effects and prevent oxidative harm, tools capable of monitoring ROS in cells and tissue in a sensitive and selective fashion are required. In this Review, a summary of existing ratiometric probes is provided, together with a critical discussion of selected examples.</description><subject>Chemistry</subject><subject>Environmental factors</subject><subject>Environmental monitoring</subject><subject>Fluorescence</subject><subject>Fluorescent indicators</subject><subject>fluorescent probes</subject><subject>Oxidants</subject><subject>Oxidizing agents</subject><subject>Probes</subject><subject>ratiometric</subject><subject>Reactive oxygen species</subject><subject>sensors</subject><subject>Species</subject><issn>0947-6539</issn><issn>1521-3765</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNqFkLlPwzAYRy0EgnKsjMgSC0uKb8cjKkcRoCKOOXLCZwhK4mInQP97jMohsTDZw_uefnoI7VIypoSww-oJ2jEjVBMmZL6CRlQymnGt5CoaESN0piQ3G2gzxmdCiFGcr6MNlktFBdcjdHFj-9q30Ie6wqfN4APECroeXwdfQsTOB9w_AT6GHqpEdtg7fAM2_V8Bz94Xj9Dh2zlUNcRttOZsE2Hn691C96cnd5Npdjk7O58cXWaV0CrPBHDIZS5Z7pwotWWMiwegRlXScCcdJ4qXhtlcKyeFtlLmQAkvFZSWCaf5FjpYeufBvwwQ-6Kt0-imsR34IRbUEMF4spqE7v9Bn_0QurQuUUJRrtKkRI2XVBV8jAFcMQ91a8OioKT4zFx8Zi5-MqeDvS_tULbw8IN_d02AWQJvdQOLf3TFZHpy9Sv_AOFwh84</recordid><startdate>20171004</startdate><enddate>20171004</enddate><creator>Andina, Diana</creator><creator>Leroux, Jean‐Christophe</creator><creator>Luciani, Paola</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20171004</creationdate><title>Ratiometric Fluorescent Probes for the Detection of Reactive Oxygen Species</title><author>Andina, Diana ; Leroux, Jean‐Christophe ; Luciani, Paola</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4768-4e3e858528ff4b7a2234de196c593f5f3063b92a876f547a558e103b6eba24f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Chemistry</topic><topic>Environmental factors</topic><topic>Environmental monitoring</topic><topic>Fluorescence</topic><topic>Fluorescent indicators</topic><topic>fluorescent probes</topic><topic>Oxidants</topic><topic>Oxidizing agents</topic><topic>Probes</topic><topic>ratiometric</topic><topic>Reactive oxygen species</topic><topic>sensors</topic><topic>Species</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Andina, Diana</creatorcontrib><creatorcontrib>Leroux, Jean‐Christophe</creatorcontrib><creatorcontrib>Luciani, Paola</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Chemistry : a European journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Andina, Diana</au><au>Leroux, Jean‐Christophe</au><au>Luciani, Paola</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ratiometric Fluorescent Probes for the Detection of Reactive Oxygen Species</atitle><jtitle>Chemistry : a European journal</jtitle><addtitle>Chemistry</addtitle><date>2017-10-04</date><risdate>2017</risdate><volume>23</volume><issue>55</issue><spage>13549</spage><epage>13573</epage><pages>13549-13573</pages><issn>0947-6539</issn><eissn>1521-3765</eissn><abstract>Reactive oxygen species (ROS) are endogenously produced oxidants with various functions ranging from host defense to signaling. These transient species can cause severe damage to the body when their production is dysregulated or when environmental factors elevate their concentrations. To study their effects and prevent oxidative harm, tools capable of monitoring ROS in cells and tissue in a sensitive and selective fashion are required. In this Review, a summary of existing ratiometric probes is provided, together with a critical discussion of selected examples.
Bright ideas: Reactive oxygen species (ROS) are endogenously produced oxidants with various functions ranging from host defense to signaling. To study their effects and prevent oxidative harm, tools capable of monitoring ROS in cells and tissue in a sensitive and selective fashion are required. In this Review, a summary of existing ratiometric probes is provided, together with a critical discussion of selected examples.</abstract><cop>Germany</cop><pub>Wiley Subscription Services, Inc</pub><pmid>28561437</pmid><doi>10.1002/chem.201702458</doi><tpages>25</tpages></addata></record> |
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| ispartof | Chemistry : a European journal, 2017-10, Vol.23 (55), p.13549-13573 |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Chemistry Environmental factors Environmental monitoring Fluorescence Fluorescent indicators fluorescent probes Oxidants Oxidizing agents Probes ratiometric Reactive oxygen species sensors Species |
| title | Ratiometric Fluorescent Probes for the Detection of Reactive Oxygen Species |
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