N-Heterocyclic carbene copper-catalyzed direct alkylation of terminal alkynes with non-activated alkyl triflates

(NHC)-Cu-catalyzed C(sp)-C(sp ) bond formation has been successfully achieved under mild conditions. Nonactivated alkyl triflates, which could be easily derived from alcohols, were utilized as C-O electrophiles. Mechanistic studies suggested that copper acetylide was the active species. Scale-up rea...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2017-04, Vol.53 (29), p.4124-4127
Hauptverfasser:	Jin, Liqun, Hao, Wangfang, Xu, Jianeng, Sun, Nan, Hu, Baoxiang, Shen, Zhenlu, Mo, Weimin, Hu, Xinquan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkylation Alkynes Bonding Carbenes Copper Efficiency Strategy Terminals
Online-Zugang:	Volltext
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