Ultralow-Fouling Behavior of Biorecognition Coatings Based on Carboxy-Functional Brushes of Zwitterionic Homo- and Copolymers in Blood Plasma: Functionalization Matters

Fouling from complex biological fluids such as blood plasma to biorecognition element (BRE)-functionalized coatings hampers the use of affinity biosensor technologies in medical diagnostics. Here, we report the effects the molecular mechanisms involved in functionalization of low-fouling carboxy-fun...

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Veröffentlicht in:	Analytical chemistry (Washington) 2017-03, Vol.89 (6), p.3524-3531
Hauptverfasser:	Lísalová, Hana, Brynda, Eduard, Houska, Milan, Víšová, Ivana, Mrkvová, Kateřina, Song, Xue Chadtová, Gedeonová, Erika, Surman, František, Riedel, Tomáš, Pop-Georgievski, Ognen, Homola, Jiří
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensors Blood Blood plasma Brushes Coated Materials, Biocompatible - chemistry Coated Materials, Biocompatible - metabolism Coatings Copolymers Deactivation Fouling Humans Methacrylamide Molecular Structure Photoelectron Spectroscopy Plasma Polychlorinated biphenyls Polymers - chemical synthesis Polymers - chemistry Polymers - metabolism
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