Histopathologic evaluation of atypical neurofibromatous tumors and their transformation into malignant peripheral nerve sheath tumor in patients with neurofibromatosis 1—a consensus overview

Patients with neurofibromatosis 1 (NF1) develop multiple neurofibromas, with 8% to 15% of patients experiencing malignant peripheral nerve sheath tumor (MPNST) during their lifetime. Prediction of transformation, typically from plexiform neurofibroma, is clinically and histologically challenging. In...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Human pathology 2017-09, Vol.67, p.1-10
Hauptverfasser:	Miettinen, Markku M., Antonescu, Cristina R., Fletcher, Christopher D.M., Kim, Aerang, Lazar, Alexander J., Quezado, Martha M., Reilly, Karlyne M., Stemmer-Rachamimov, Anat, Stewart, Douglas R., Viskochil, David, Widemann, Brigitte, Perry, Arie
Format:	Artikel
Sprache:	eng
Schlagworte:	Atypia Biomarkers, Tumor - analysis Biopsy Cancer Cell cycle Cell Nucleus - pathology Consensus Disease Progression Genetic disorders Humans Immunohistochemistry Malignant peripheral nerve sheath tumor Mitosis Mutation Neoplasm Grading Neurilemmoma - chemistry Neurilemmoma - classification Neurilemmoma - pathology Neurofibroma Neurofibromatosis 1 Neurofibromatosis 1 - classification Neurofibromatosis 1 - metabolism Neurofibromatosis 1 - pathology Neurological disorders NMR Nuclear magnetic resonance Pathology Predictive Value of Tests Terminology as Topic Tomography Transformation Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!