Morphological evaluation of retinal ganglion cells expressing the L132C/T159C ChR2 mutant transgene in young adult cynomolgus monkeys

To characterize recombinant AAV2 （rAAV2）-mediated expression of L 132C/T 159C ChR2 mutant in retinal ganglion cells （RGCs） of young adult cynomolgus monkeys, rAAV2 vectors carrying a fusion construct of the ChR2 mutant and GFP （ChR2-GFP） were delivered to the vitreous chamber by intravitreal injecti...

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Veröffentlicht in:	Science China. Life sciences 2017-11, Vol.60 (11), p.1157-1167
Hauptverfasser:	Wang, Wenyao, Nan, Yan, Pan, Zhuo-Hua, Pu, Mingliang
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Injection Life Sciences Research Paper Retina Retinal ganglion cells Ribonucleic acid RNA RNA-binding protein Splicing Transgenes Young adults
Online-Zugang:	Volltext
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