Nogo‐B is the major form of Nogo at the floor plate and likely mediates crossing of commissural axons in the mouse spinal cord

Using Nogo antibodies with defined binding specificity, Nogo‐B, but not Nogo‐A, was localized on radial glia in the floor plate of mouse embryos. The presence of Nogo‐B was confirmed in Nogo‐A knockout mice. In explant cultures of embryonic day (E) 11 and E12 spinal cord, blocking of NgR function wi...

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