Effect of Albiglutide on Cholecystokinin‐Induced Gallbladder Emptying in Healthy Individuals: A Randomized Crossover Study

The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) exenatide and lixisenatide reduce cholecystokinin (CCK)‐induced gallbladder emptying in healthy subjects. It is unknown if all GLP‐1 RAs share this effect; therefore, the effect of the GLP‐1 RA albiglutide on gallbladder function was assess...

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Veröffentlicht in:	Journal of clinical pharmacology 2017-10, Vol.57 (10), p.1322-1329
Hauptverfasser:	Shaddinger, Bonnie C., Young, Malcolm A., Billiard, Julia, Collins, David A., Hussaini, Azra, Nino, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult albiglutide Cholecystokinin Cross-Over Studies Double-Blind Method Emptying Female Gallbladder Gallbladder - diagnostic imaging Gallbladder - drug effects gallbladder ejection fraction gallbladder emptying Gallbladder Emptying - drug effects GLP-1 receptor agonists Glucagon-Like Peptide 1 - adverse effects Glucagon-Like Peptide 1 - analogs & derivatives Glucagon-Like Peptide 1 - blood Glucagon-Like Peptide 1 - pharmacokinetics Glucagon-Like Peptide 1 - pharmacology Glucagon-Like Peptide-1 Receptor - agonists glucagon‐like peptide‐1 receptor agonist Humans incretin Male Middle Aged Randomization Ultrasonography Young Adult
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