Effects of supplementation with quercetin on plasma C-reactive protein concentrations: a systematic review and meta-analysis of randomized controlled trials
Promising experimental studies suggest that quercetin has potential anti-inflammatory effects. However, the results of current clinical trials on quercetin’s effects on the C-reactive protein (CRP), a sensitive inflammatory biomarker, are ambiguous. We conducted a meta-analysis of available randomiz...
Gespeichert in:
| Veröffentlicht in: | European journal of clinical nutrition 2017-09, Vol.71 (9), p.1033-1039 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1039 |
|---|---|
| container_issue | 9 |
| container_start_page | 1033 |
| container_title | European journal of clinical nutrition |
| container_volume | 71 |
| creator | Mohammadi-Sartang, M Mazloom, Z Sherafatmanesh, S Ghorbani, M Firoozi, Donya |
| description | Promising experimental studies suggest that quercetin has potential anti-inflammatory effects. However, the results of current clinical trials on quercetin’s effects on the C-reactive protein (CRP), a sensitive inflammatory biomarker, are ambiguous. We conducted a meta-analysis of available randomized controlled trials (RCTs) to resolve this inconsistency and quantify the net effect of quercetin on circulating CRP concentrations. A systematic search was performed in several databases including SCOPUS, PubMed–Medline and Google Scholar until 16 June 2016. We used a random-effects model in combination with weight mean difference (WMD) and 95% confidence intervals (CI) for data analysis. Standard methods were used for the assessment of heterogeneity, meta-regression, sensitivity analysis and publication bias. The meta-analysis of seven RCTs (10 treatment arms) showed a significant reduction of circulating CRP levels (WMD: −0.33 mg/l; 95% CI: −0.50 to −0.15;
P |
| doi_str_mv | 10.1038/ejcn.2017.55 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1902114635</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A503411138</galeid><sourcerecordid>A503411138</sourcerecordid><originalsourceid>FETCH-LOGICAL-c521t-4f4d6221656b269b8edd7c7d8e1ef56e5c73d18fc3e88478541c0747e8d3e2753</originalsourceid><addsrcrecordid>eNp9kk1vEzEQhlcIREPhxhlZQkIcusEf67XDrYpKQarEBc6W451NHHntYHtbhd_Cj8WbFtqiCPkw9swzM5rXU1WvCZ4TzOQH2Bo_p5iIOedPqhlpRFvztsFPqxle8KZmGIuT6kVKW4xLUNDn1QmVnAku8az6ddH3YHJCoUdp3O0cDOCzzjZ4dGPzBv0YIRrI1qPi2TmdBo2WdQRtsr0GtIshQwma4E1JjIfM9BFplPYpw1DeBkW4tnCDtO_QAFnX2mu3T_bQNBZvGOxP6KYaOQbnyjVHq116WT3ri4FXd_a0-v7p4tvyc3319fLL8vyqNpySXDd907WUkpa3K9ouVhK6ThjRSSDQ8xa4EawjsjcMpGyE5A0xWDQCZMeACs5Oq_e3dcs0Zd6U1WCTAee0hzAmRRaYEtK0bELf_oNuwxjLPEnRlnDOKF38lyILVoSnkuJ7aq0dKOv7UPQzU2t1zjFrCCFMFqo-Qq3BQ9QueOhtcT_i50f4cjoYrDma8O5Bwga0y5sU3Hj4ycfg2S1oYkgpQq920Q467hXBatpFNe2imnZR8UmEN3cijKsBur_wn-W7nyyVkF9DfKDSsYK_AXEm6Is</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1935802820</pqid></control><display><type>article</type><title>Effects of supplementation with quercetin on plasma C-reactive protein concentrations: a systematic review and meta-analysis of randomized controlled trials</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Mohammadi-Sartang, M ; Mazloom, Z ; Sherafatmanesh, S ; Ghorbani, M ; Firoozi, Donya</creator><creatorcontrib>Mohammadi-Sartang, M ; Mazloom, Z ; Sherafatmanesh, S ; Ghorbani, M ; Firoozi, Donya</creatorcontrib><description>Promising experimental studies suggest that quercetin has potential anti-inflammatory effects. However, the results of current clinical trials on quercetin’s effects on the C-reactive protein (CRP), a sensitive inflammatory biomarker, are ambiguous. We conducted a meta-analysis of available randomized controlled trials (RCTs) to resolve this inconsistency and quantify the net effect of quercetin on circulating CRP concentrations. A systematic search was performed in several databases including SCOPUS, PubMed–Medline and Google Scholar until 16 June 2016. We used a random-effects model in combination with weight mean difference (WMD) and 95% confidence intervals (CI) for data analysis. Standard methods were used for the assessment of heterogeneity, meta-regression, sensitivity analysis and publication bias. The meta-analysis of seven RCTs (10 treatment arms) showed a significant reduction of circulating CRP levels (WMD: −0.33 mg/l; 95% CI: −0.50 to −0.15;
P
<0.001) following quercetin supplementation. In the subgroup analysis, a significant reducing effect was observed in trials with ⩾500 mg/day dosage (WMD: −0.34 mg/l; 95% CI: −0.52, −0.16;
P
⩽0.001) and in those with CRP <3 mg/l (WMD: −0.34 mg/l; 95% CI: −0.51, −0.18;
P⩽
0.001). In meta-regression, there was no association between changes in CRP concentrations, dose of supplementation and CRP baseline values. Our findings showed a significant effect of quercetin supplementation on the C-reactive protein—especially at doses above 500 mg/day and in patients with CRP <3 mg/l.</description><identifier>ISSN: 0954-3007</identifier><identifier>EISSN: 1476-5640</identifier><identifier>DOI: 10.1038/ejcn.2017.55</identifier><identifier>PMID: 28537580</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/499 ; 692/53 ; Antioxidants - pharmacology ; Biomarkers ; Biomarkers - metabolism ; C-reactive protein ; C-Reactive Protein - metabolism ; Clinical Nutrition ; Clinical trials ; Confidence intervals ; Data analysis ; Data processing ; Dietary Supplements ; Dosage ; Epidemiology ; Health aspects ; Heterogeneity ; Humans ; Inflammation ; Internal Medicine ; Medical research ; Medicine ; Medicine & Public Health ; Meta-analysis ; Metabolic Diseases ; Nutrition Therapy ; Polyphenols ; Proteins ; Public Health ; Quercetin ; Quercetin - pharmacology ; Randomization ; Randomized Controlled Trials as Topic ; Regression analysis ; review ; Scientific papers ; Search engines ; Sensitivity analysis ; Statistical analysis ; Subgroups ; Supplements</subject><ispartof>European journal of clinical nutrition, 2017-09, Vol.71 (9), p.1033-1039</ispartof><rights>Macmillan Publishers Limited, part of Springer Nature. 2017</rights><rights>COPYRIGHT 2017 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Sep 2017</rights><rights>Macmillan Publishers Limited, part of Springer Nature. 2017.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c521t-4f4d6221656b269b8edd7c7d8e1ef56e5c73d18fc3e88478541c0747e8d3e2753</citedby><cites>FETCH-LOGICAL-c521t-4f4d6221656b269b8edd7c7d8e1ef56e5c73d18fc3e88478541c0747e8d3e2753</cites><orcidid>0000-0003-2417-7700</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/ejcn.2017.55$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/ejcn.2017.55$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27922,27923,41486,42555,51317</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28537580$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mohammadi-Sartang, M</creatorcontrib><creatorcontrib>Mazloom, Z</creatorcontrib><creatorcontrib>Sherafatmanesh, S</creatorcontrib><creatorcontrib>Ghorbani, M</creatorcontrib><creatorcontrib>Firoozi, Donya</creatorcontrib><title>Effects of supplementation with quercetin on plasma C-reactive protein concentrations: a systematic review and meta-analysis of randomized controlled trials</title><title>European journal of clinical nutrition</title><addtitle>Eur J Clin Nutr</addtitle><addtitle>Eur J Clin Nutr</addtitle><description>Promising experimental studies suggest that quercetin has potential anti-inflammatory effects. However, the results of current clinical trials on quercetin’s effects on the C-reactive protein (CRP), a sensitive inflammatory biomarker, are ambiguous. We conducted a meta-analysis of available randomized controlled trials (RCTs) to resolve this inconsistency and quantify the net effect of quercetin on circulating CRP concentrations. A systematic search was performed in several databases including SCOPUS, PubMed–Medline and Google Scholar until 16 June 2016. We used a random-effects model in combination with weight mean difference (WMD) and 95% confidence intervals (CI) for data analysis. Standard methods were used for the assessment of heterogeneity, meta-regression, sensitivity analysis and publication bias. The meta-analysis of seven RCTs (10 treatment arms) showed a significant reduction of circulating CRP levels (WMD: −0.33 mg/l; 95% CI: −0.50 to −0.15;
P
<0.001) following quercetin supplementation. In the subgroup analysis, a significant reducing effect was observed in trials with ⩾500 mg/day dosage (WMD: −0.34 mg/l; 95% CI: −0.52, −0.16;
P
⩽0.001) and in those with CRP <3 mg/l (WMD: −0.34 mg/l; 95% CI: −0.51, −0.18;
P⩽
0.001). In meta-regression, there was no association between changes in CRP concentrations, dose of supplementation and CRP baseline values. Our findings showed a significant effect of quercetin supplementation on the C-reactive protein—especially at doses above 500 mg/day and in patients with CRP <3 mg/l.</description><subject>692/499</subject><subject>692/53</subject><subject>Antioxidants - pharmacology</subject><subject>Biomarkers</subject><subject>Biomarkers - metabolism</subject><subject>C-reactive protein</subject><subject>C-Reactive Protein - metabolism</subject><subject>Clinical Nutrition</subject><subject>Clinical trials</subject><subject>Confidence intervals</subject><subject>Data analysis</subject><subject>Data processing</subject><subject>Dietary Supplements</subject><subject>Dosage</subject><subject>Epidemiology</subject><subject>Health aspects</subject><subject>Heterogeneity</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Internal Medicine</subject><subject>Medical research</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Meta-analysis</subject><subject>Metabolic Diseases</subject><subject>Nutrition Therapy</subject><subject>Polyphenols</subject><subject>Proteins</subject><subject>Public Health</subject><subject>Quercetin</subject><subject>Quercetin - pharmacology</subject><subject>Randomization</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Regression analysis</subject><subject>review</subject><subject>Scientific papers</subject><subject>Search engines</subject><subject>Sensitivity analysis</subject><subject>Statistical analysis</subject><subject>Subgroups</subject><subject>Supplements</subject><issn>0954-3007</issn><issn>1476-5640</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kk1vEzEQhlcIREPhxhlZQkIcusEf67XDrYpKQarEBc6W451NHHntYHtbhd_Cj8WbFtqiCPkw9swzM5rXU1WvCZ4TzOQH2Bo_p5iIOedPqhlpRFvztsFPqxle8KZmGIuT6kVKW4xLUNDn1QmVnAku8az6ddH3YHJCoUdp3O0cDOCzzjZ4dGPzBv0YIRrI1qPi2TmdBo2WdQRtsr0GtIshQwma4E1JjIfM9BFplPYpw1DeBkW4tnCDtO_QAFnX2mu3T_bQNBZvGOxP6KYaOQbnyjVHq116WT3ri4FXd_a0-v7p4tvyc3319fLL8vyqNpySXDd907WUkpa3K9ouVhK6ThjRSSDQ8xa4EawjsjcMpGyE5A0xWDQCZMeACs5Oq_e3dcs0Zd6U1WCTAee0hzAmRRaYEtK0bELf_oNuwxjLPEnRlnDOKF38lyILVoSnkuJ7aq0dKOv7UPQzU2t1zjFrCCFMFqo-Qq3BQ9QueOhtcT_i50f4cjoYrDma8O5Bwga0y5sU3Hj4ycfg2S1oYkgpQq920Q467hXBatpFNe2imnZR8UmEN3cijKsBur_wn-W7nyyVkF9DfKDSsYK_AXEm6Is</recordid><startdate>20170901</startdate><enddate>20170901</enddate><creator>Mohammadi-Sartang, M</creator><creator>Mazloom, Z</creator><creator>Sherafatmanesh, S</creator><creator>Ghorbani, M</creator><creator>Firoozi, Donya</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7TK</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2417-7700</orcidid></search><sort><creationdate>20170901</creationdate><title>Effects of supplementation with quercetin on plasma C-reactive protein concentrations: a systematic review and meta-analysis of randomized controlled trials</title><author>Mohammadi-Sartang, M ; Mazloom, Z ; Sherafatmanesh, S ; Ghorbani, M ; Firoozi, Donya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c521t-4f4d6221656b269b8edd7c7d8e1ef56e5c73d18fc3e88478541c0747e8d3e2753</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>692/499</topic><topic>692/53</topic><topic>Antioxidants - pharmacology</topic><topic>Biomarkers</topic><topic>Biomarkers - metabolism</topic><topic>C-reactive protein</topic><topic>C-Reactive Protein - metabolism</topic><topic>Clinical Nutrition</topic><topic>Clinical trials</topic><topic>Confidence intervals</topic><topic>Data analysis</topic><topic>Data processing</topic><topic>Dietary Supplements</topic><topic>Dosage</topic><topic>Epidemiology</topic><topic>Health aspects</topic><topic>Heterogeneity</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Internal Medicine</topic><topic>Medical research</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Meta-analysis</topic><topic>Metabolic Diseases</topic><topic>Nutrition Therapy</topic><topic>Polyphenols</topic><topic>Proteins</topic><topic>Public Health</topic><topic>Quercetin</topic><topic>Quercetin - pharmacology</topic><topic>Randomization</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Regression analysis</topic><topic>review</topic><topic>Scientific papers</topic><topic>Search engines</topic><topic>Sensitivity analysis</topic><topic>Statistical analysis</topic><topic>Subgroups</topic><topic>Supplements</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mohammadi-Sartang, M</creatorcontrib><creatorcontrib>Mazloom, Z</creatorcontrib><creatorcontrib>Sherafatmanesh, S</creatorcontrib><creatorcontrib>Ghorbani, M</creatorcontrib><creatorcontrib>Firoozi, Donya</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection (ProQuest)</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of clinical nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mohammadi-Sartang, M</au><au>Mazloom, Z</au><au>Sherafatmanesh, S</au><au>Ghorbani, M</au><au>Firoozi, Donya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of supplementation with quercetin on plasma C-reactive protein concentrations: a systematic review and meta-analysis of randomized controlled trials</atitle><jtitle>European journal of clinical nutrition</jtitle><stitle>Eur J Clin Nutr</stitle><addtitle>Eur J Clin Nutr</addtitle><date>2017-09-01</date><risdate>2017</risdate><volume>71</volume><issue>9</issue><spage>1033</spage><epage>1039</epage><pages>1033-1039</pages><issn>0954-3007</issn><eissn>1476-5640</eissn><abstract>Promising experimental studies suggest that quercetin has potential anti-inflammatory effects. However, the results of current clinical trials on quercetin’s effects on the C-reactive protein (CRP), a sensitive inflammatory biomarker, are ambiguous. We conducted a meta-analysis of available randomized controlled trials (RCTs) to resolve this inconsistency and quantify the net effect of quercetin on circulating CRP concentrations. A systematic search was performed in several databases including SCOPUS, PubMed–Medline and Google Scholar until 16 June 2016. We used a random-effects model in combination with weight mean difference (WMD) and 95% confidence intervals (CI) for data analysis. Standard methods were used for the assessment of heterogeneity, meta-regression, sensitivity analysis and publication bias. The meta-analysis of seven RCTs (10 treatment arms) showed a significant reduction of circulating CRP levels (WMD: −0.33 mg/l; 95% CI: −0.50 to −0.15;
P
<0.001) following quercetin supplementation. In the subgroup analysis, a significant reducing effect was observed in trials with ⩾500 mg/day dosage (WMD: −0.34 mg/l; 95% CI: −0.52, −0.16;
P
⩽0.001) and in those with CRP <3 mg/l (WMD: −0.34 mg/l; 95% CI: −0.51, −0.18;
P⩽
0.001). In meta-regression, there was no association between changes in CRP concentrations, dose of supplementation and CRP baseline values. Our findings showed a significant effect of quercetin supplementation on the C-reactive protein—especially at doses above 500 mg/day and in patients with CRP <3 mg/l.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>28537580</pmid><doi>10.1038/ejcn.2017.55</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-2417-7700</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0954-3007 |
| ispartof | European journal of clinical nutrition, 2017-09, Vol.71 (9), p.1033-1039 |
| issn | 0954-3007 1476-5640 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1902114635 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | 692/499 692/53 Antioxidants - pharmacology Biomarkers Biomarkers - metabolism C-reactive protein C-Reactive Protein - metabolism Clinical Nutrition Clinical trials Confidence intervals Data analysis Data processing Dietary Supplements Dosage Epidemiology Health aspects Heterogeneity Humans Inflammation Internal Medicine Medical research Medicine Medicine & Public Health Meta-analysis Metabolic Diseases Nutrition Therapy Polyphenols Proteins Public Health Quercetin Quercetin - pharmacology Randomization Randomized Controlled Trials as Topic Regression analysis review Scientific papers Search engines Sensitivity analysis Statistical analysis Subgroups Supplements |
| title | Effects of supplementation with quercetin on plasma C-reactive protein concentrations: a systematic review and meta-analysis of randomized controlled trials |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T13%3A55%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20supplementation%20with%20quercetin%20on%20plasma%20C-reactive%20protein%20concentrations:%20a%20systematic%20review%20and%20meta-analysis%20of%20randomized%20controlled%20trials&rft.jtitle=European%20journal%20of%20clinical%20nutrition&rft.au=Mohammadi-Sartang,%20M&rft.date=2017-09-01&rft.volume=71&rft.issue=9&rft.spage=1033&rft.epage=1039&rft.pages=1033-1039&rft.issn=0954-3007&rft.eissn=1476-5640&rft_id=info:doi/10.1038/ejcn.2017.55&rft_dat=%3Cgale_proqu%3EA503411138%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1935802820&rft_id=info:pmid/28537580&rft_galeid=A503411138&rfr_iscdi=true |