Study of the Hetero-[4+2]-Cycloaddition Reaction of Aldimines and Alkynes. Synthesis of 1,5-Naphthyridine and Isoindolone Derivatives

Both experimental and computational studies for the cycloaddition reaction between N-(3-pyridyl)­aldimines and acetylenes where 1,5-naphthyridines are obtained are reported. The reaction of benzaldimine with a methoxycarbonyl group in position 2 with phenyl acetylene, styrene, and indene afforded po...

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Veröffentlicht in:Journal of organic chemistry 2017-06, Vol.82 (12), p.6379-6387
Hauptverfasser: Alonso, Concepción, González, María, Palacios, Francisco, Rubiales, Gloria
Format: Artikel
Sprache:eng
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