Role of X‑linked inhibitor of apoptosis‑associated factor‑1 in vasculogenic mimicry in ovarian cancer

X-linked inhibitor of apoptosis‑associated factor 1 (XAF1) was identified as a novel X-linked inhibitor of apoptosis (XIAP) binding partner that may reverse the anti‑apoptotic effect of XIAP. Previous studies have revealed that XAF1 serves an important role in cancer angiogenesis. Vasculogenic mimic...

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Veröffentlicht in:	Molecular medicine reports 2017-07, Vol.16 (1), p.325-330
Hauptverfasser:	Wang, Yunxia, Liu, Peishu, Wang, Xietong, Mao, Hongluan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis Angiogenesis Animals Apoptosis Biomarkers Cancer metastasis Cancer therapies Care and treatment Cell Line, Tumor Cell migration Cell Movement - genetics Disease Models, Animal Female Gene Expression Health aspects Heterografts Humans Immunohistochemistry Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Invasiveness Liver cancer Lymphatic Metastasis Medical prognosis Metastases Mice Middle Aged Mimicry Neoplasm Grading Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Neoplasm Staging Neovascularization, Pathologic - genetics Neovascularization, Pathologic - metabolism Ovarian cancer Ovarian carcinoma Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Pathology Patients Platelet Endothelial Cell Adhesion Molecule-1 - metabolism Tumor cells Tumor necrosis factor-TNF Vascular endothelial growth factor X-Linked Inhibitor of Apoptosis Protein - metabolism Xenografts XIAP protein
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