Base-Induced Transformation of 2‑Acyl-3-alkyl‑2H‑azirines to Oxazoles: Involvement of Deprotonation-Initiated Pathways

An experimental study of base-induced transformation reaction of 2-acyl-3-alkyl-2H-azirines to oxazoles indicated that a deprotonation-initiated mechanism is involved, in addition to nucleophilic addition to the imine functionality. Calculations suggested the participation of a ketenimine (ethenimin...

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Veröffentlicht in:	Journal of organic chemistry 2017-06, Vol.82 (12), p.6313-6326
Hauptverfasser:	Ning, Yingtang, Otani, Yuko, Ohwada, Tomohiko
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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