Angubindin-1, a novel paracellular absorption enhancer acting at the tricellular tight junction

A limiting barrier for mucosal absorption of drugs is the tight junction (TJ). TJs exist between two adjacent cells (bicellular TJ, bTJ) and at the sites where three cells meet (tricellular TJ, tTJ). We present a novel approach which employs a physiologically regulated pathway for the passage of lar...

Ausführliche Beschreibung