Primary Cutaneous Mucormycosis in an Extremely Preterm Infant Successfully Treated with Liposomal Amphotericin B
Cutaneous mucormycosis is a rare but often fatal invasive fungal infection that occurs most commonly in patients with diabetes, malignancy, and other immunocompromising conditions. We report an extremely preterm (
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| Veröffentlicht in: | Pediatric dermatology 2017-05, Vol.34 (3), p.e116-e119 |
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| container_end_page | e119 |
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| container_title | Pediatric dermatology |
| container_volume | 34 |
| creator | Lowe, Christopher D. Sainato, Rebecca J. Stagliano, David R. Morgan, Maribel M. Green, Brian P. |
| description | Cutaneous mucormycosis is a rare but often fatal invasive fungal infection that occurs most commonly in patients with diabetes, malignancy, and other immunocompromising conditions. We report an extremely preterm ( |
| doi_str_mv | 10.1111/pde.13124 |
| format | Article |
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We report an extremely preterm (<28 weeks) baby boy who developed polymicrobial sepsis and primary cutaneous mucormycosis within his first 10 days of life. He was successfully treated with medical management alone since he was not a candidate for surgery. Successful treatment of cutaneous mucormycosis without surgical debridement has been reported on only two other occasions. 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This case highlights the importance of rapid and thorough evaluation of skin lesions when evaluating preterm infants and other immunocompromised patients, even when other sources of infection have been identified.</description><subject>Amphotericin B</subject><subject>Amphotericin B - therapeutic use</subject><subject>Antifungal agents</subject><subject>Antifungal Agents - therapeutic use</subject><subject>Baby foods</subject><subject>Case reports</subject><subject>Dermatomycoses - diagnosis</subject><subject>Dermatomycoses - drug therapy</subject><subject>Dermatomycoses - microbiology</subject><subject>Diabetes mellitus</subject><subject>Follow-Up Studies</subject><subject>Fungal infections</subject><subject>Humans</subject><subject>Immunocompromised hosts</subject><subject>Infant, Extremely Premature</subject><subject>Infant, Newborn</subject><subject>Infants</subject><subject>Male</subject><subject>Malignancy</subject><subject>Monitoring, Physiologic</subject><subject>Mucormycosis</subject><subject>Mucormycosis - drug therapy</subject><subject>Mucormycosis - microbiology</subject><subject>Premature babies</subject><subject>Rhizopus - ultrastructure</subject><subject>Risk Assessment</subject><subject>Sepsis</subject><subject>Skin diseases</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><issn>0736-8046</issn><issn>1525-1470</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kV1LwzAYhYMobk4v_AMS8EYvuuWjH-nlnFMHEwfO65Klb1lH29SkZfbfG-30QjA3LyTPe8g5B6FLSsbUnUmdwphyyvwjNKQBCzzqR-QYDUnEQ08QPxygM2t3hBARhvQUDZgIGBexP0T1yuSlNB2etY2sQLcWP7dKm7JT2uYW5xWWFZ5_NAZKKDq8MtCAKfGiymTV4NdWKbA2awv3tjYgG0jxPm-2eJnX2upSFnha1lvtlnLlxO7O0UkmCwsXhzlCbw_z9ezJW748LmbTpad4wH3nAGTKiIx8EfJAch5GNJKEZzQjQQqpYIHMxEY5Q4T4NGV-KoXkIYONdFfAR-im162Nfm_BNkmZWwVF0btMaOzS4DEVsUOv_6A73ZrK_c5RjARcMEIdddtTymhrDWRJ3UeXUJJ81ZC4GpLvGhx7dVBsNyWkv-RP7g6Y9MA-L6D7XylZ3c97yU-CWJGD</recordid><startdate>201705</startdate><enddate>201705</enddate><creator>Lowe, Christopher D.</creator><creator>Sainato, Rebecca J.</creator><creator>Stagliano, David R.</creator><creator>Morgan, Maribel M.</creator><creator>Green, Brian P.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>201705</creationdate><title>Primary Cutaneous Mucormycosis in an Extremely Preterm Infant Successfully Treated with Liposomal Amphotericin B</title><author>Lowe, Christopher D. ; Sainato, Rebecca J. ; Stagliano, David R. ; Morgan, Maribel M. ; Green, Brian P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3534-14ead20a748635a336717a03f1f05ded825af8bc8660041d24da8a362eba660e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Amphotericin B</topic><topic>Amphotericin B - therapeutic use</topic><topic>Antifungal agents</topic><topic>Antifungal Agents - therapeutic use</topic><topic>Baby foods</topic><topic>Case reports</topic><topic>Dermatomycoses - diagnosis</topic><topic>Dermatomycoses - drug therapy</topic><topic>Dermatomycoses - microbiology</topic><topic>Diabetes mellitus</topic><topic>Follow-Up Studies</topic><topic>Fungal infections</topic><topic>Humans</topic><topic>Immunocompromised hosts</topic><topic>Infant, Extremely Premature</topic><topic>Infant, Newborn</topic><topic>Infants</topic><topic>Male</topic><topic>Malignancy</topic><topic>Monitoring, Physiologic</topic><topic>Mucormycosis</topic><topic>Mucormycosis - drug therapy</topic><topic>Mucormycosis - microbiology</topic><topic>Premature babies</topic><topic>Rhizopus - ultrastructure</topic><topic>Risk Assessment</topic><topic>Sepsis</topic><topic>Skin diseases</topic><topic>Surgery</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lowe, Christopher D.</creatorcontrib><creatorcontrib>Sainato, Rebecca J.</creatorcontrib><creatorcontrib>Stagliano, David R.</creatorcontrib><creatorcontrib>Morgan, Maribel M.</creatorcontrib><creatorcontrib>Green, Brian P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lowe, Christopher D.</au><au>Sainato, Rebecca J.</au><au>Stagliano, David R.</au><au>Morgan, Maribel M.</au><au>Green, Brian P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary Cutaneous Mucormycosis in an Extremely Preterm Infant Successfully Treated with Liposomal Amphotericin B</atitle><jtitle>Pediatric dermatology</jtitle><addtitle>Pediatr Dermatol</addtitle><date>2017-05</date><risdate>2017</risdate><volume>34</volume><issue>3</issue><spage>e116</spage><epage>e119</epage><pages>e116-e119</pages><issn>0736-8046</issn><eissn>1525-1470</eissn><abstract>Cutaneous mucormycosis is a rare but often fatal invasive fungal infection that occurs most commonly in patients with diabetes, malignancy, and other immunocompromising conditions. We report an extremely preterm (<28 weeks) baby boy who developed polymicrobial sepsis and primary cutaneous mucormycosis within his first 10 days of life. He was successfully treated with medical management alone since he was not a candidate for surgery. Successful treatment of cutaneous mucormycosis without surgical debridement has been reported on only two other occasions. This case highlights the importance of rapid and thorough evaluation of skin lesions when evaluating preterm infants and other immunocompromised patients, even when other sources of infection have been identified.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>28523894</pmid><doi>10.1111/pde.13124</doi><tpages>4</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Amphotericin B Amphotericin B - therapeutic use Antifungal agents Antifungal Agents - therapeutic use Baby foods Case reports Dermatomycoses - diagnosis Dermatomycoses - drug therapy Dermatomycoses - microbiology Diabetes mellitus Follow-Up Studies Fungal infections Humans Immunocompromised hosts Infant, Extremely Premature Infant, Newborn Infants Male Malignancy Monitoring, Physiologic Mucormycosis Mucormycosis - drug therapy Mucormycosis - microbiology Premature babies Rhizopus - ultrastructure Risk Assessment Sepsis Skin diseases Surgery Treatment Outcome |
| title | Primary Cutaneous Mucormycosis in an Extremely Preterm Infant Successfully Treated with Liposomal Amphotericin B |
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