MicroRNA in skin diseases
MicroRNAs are essential regulators of various cellular processes such as cell growth, differentiation, apoptosis, and the immune response, acting as factors for translational repression and/or degradation of target messenger RNA. Currently, microRNAs are considered as promising biomarkers and therap...
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| Veröffentlicht in: | EJD. European journal of dermatology 2017-08, Vol.27 (4), p.343-352 |
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| container_title | EJD. European journal of dermatology |
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| creator | Ruksha, Tatiana G. Komina, Anna V. Palkina, Nadezhda V. |
| description | MicroRNAs are essential regulators of various cellular processes such as cell growth, differentiation, apoptosis, and the immune response, acting as factors for translational repression and/or degradation of target messenger RNA. Currently, microRNAs are considered as promising biomarkers and therapeutic targets for different pathological conditions. Skin may serve as a convenient model for microRNAmodulation studies due to the comparatively easy access to targets cells. Cutaneous diseases are characterized by multiple intercellular communication pathways, triggered by diverse stimuli and mediated by heterogenous regulators, including microRNAs. The goal of this article is to summarize the state of research in dermatology concerning the action of microRNAs as epigenetic modulators. |
| doi_str_mv | 10.1684/ejd.2017.3024 |
| format | Article |
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| issn | 1167-1122 1952-4013 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Dermatitis, Allergic Contact - genetics Dermatitis, Atopic - genetics Dermatology Epigenesis, Genetic Humans Lichen Planus - genetics Medicine Medicine & Public Health MicroRNAs - genetics Psoriasis - genetics Review Scleroderma, Localized - genetics Skin Diseases - genetics Skin Neoplasms - genetics Vitiligo - genetics |
| title | MicroRNA in skin diseases |
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