Apurinic/apyrimidinic endonuclease 1 (APE1) is overexpressed in malignant transformation of salivary gland pleomorphic adenoma

DNA repair systems play a critical role in protecting the human genome against cumulative damage. The apurinic/apyrimidinic endonuclease 1 is a protein involved in DNA base excision repair and its expression still needs to be investigated in salivary gland tumors. The objective of this study is to a...

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Veröffentlicht in:	European archives of oto-rhino-laryngology 2017-08, Vol.274 (8), p.3203-3209
Hauptverfasser:	Silva, Leorik Pereira, Santana, Thalita, Sedassari, Bruno Tavares, de Sousa, Suzana Machado, Sobral, Ana Paula Veras, Freitas, Roseana de Almeida, Barboza, Carlos Augusto Galvão, de Souza, Lélia Batista
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma, Pleomorphic - genetics Adenoma, Pleomorphic - pathology Adult Carcinoma - genetics Carcinoma - pathology Cell Transformation, Neoplastic - genetics DNA-(Apurinic or Apyrimidinic Site) Lyase - genetics Female Gene Expression Profiling Head and Neck Head and Neck Surgery Humans Immunohistochemistry Male Medicine Medicine & Public Health Middle Aged Neurosurgery Otorhinolaryngology Predictive Value of Tests Proteomics - methods Salivary Gland Neoplasms - genetics Salivary Gland Neoplasms - pathology Salivary Glands - pathology
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