Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women

In this multicenter, randomized trial involving infertile women undergoing hysterosalpingography, rates of ongoing pregnancy at 6 months and subsequent live births were higher with the use of oil contrast than with the use of water contrast. Infertility, which is defined as the inability to conceive...

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Veröffentlicht in:The New England journal of medicine 2017-05, Vol.376 (21), p.2043-2052
Hauptverfasser: Dreyer, Kim, van Rijswijk, Joukje, Mijatovic, Velja, Goddijn, Mariëtte, Verhoeve, Harold R, van Rooij, Ilse A.J, Hoek, Annemieke, Bourdrez, Petra, Nap, Annemiek W, Rijnsaardt-Lukassen, Henrike G.M, Timmerman, Catharina C.M, Kaplan, Mesrure, Hooker, Angelo B, Gijsen, Anna P, van Golde, Ron, van Heteren, Cathelijne F, Sluijmer, Alexander V, de Bruin, Jan-Peter, Smeenk, Jesper M.J, de Boer, Jacoba A.M, Scheenjes, Eduard, Duijn, Annette E.J, Mozes, Alexander, Pelinck, Marie J, Traas, Maaike A.F, van Hooff, Machiel H.A, van Unnik, Gijsbertus A, de Koning, Cornelia H, van Geloven, Nan, Twisk, Jos W.R, Hompes, Peter G.A, Mol, Ben W.J
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container_end_page 2052
container_issue 21
container_start_page 2043
container_title The New England journal of medicine
container_volume 376
creator Dreyer, Kim
van Rijswijk, Joukje
Mijatovic, Velja
Goddijn, Mariëtte
Verhoeve, Harold R
van Rooij, Ilse A.J
Hoek, Annemieke
Bourdrez, Petra
Nap, Annemiek W
Rijnsaardt-Lukassen, Henrike G.M
Timmerman, Catharina C.M
Kaplan, Mesrure
Hooker, Angelo B
Gijsen, Anna P
van Golde, Ron
van Heteren, Cathelijne F
Sluijmer, Alexander V
de Bruin, Jan-Peter
Smeenk, Jesper M.J
de Boer, Jacoba A.M
Scheenjes, Eduard
Duijn, Annette E.J
Mozes, Alexander
Pelinck, Marie J
Traas, Maaike A.F
van Hooff, Machiel H.A
van Unnik, Gijsbertus A
de Koning, Cornelia H
van Geloven, Nan
Twisk, Jos W.R
Hompes, Peter G.A
Mol, Ben W.J
description In this multicenter, randomized trial involving infertile women undergoing hysterosalpingography, rates of ongoing pregnancy at 6 months and subsequent live births were higher with the use of oil contrast than with the use of water contrast. Infertility, which is defined as the inability to conceive after 1 year of unprotected intercourse, affects approximately one of every six couples who are trying to get pregnant. 1 Hysterosalpingography to assess tubal patency is part of the infertility evaluation in many cases. Although hysterosalpingography was introduced as a diagnostic test, it has been suggested that tubal flushing directly increases pregnancy rates in the months after hysterosalpingography. 2 Many studies have shown a fertility-enhancing effect of hysterosalpingography with the use of oil contrast, 3 but few randomized, controlled trials have assessed this effect. 4 – 6 A meta-analysis of three trials showed higher rates of . . .
doi_str_mv 10.1056/NEJMoa1612337
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identifier ISSN: 0028-4793
ispartof The New England journal of medicine, 2017-05, Vol.376 (21), p.2043-2052
issn 0028-4793
1533-4406
language eng
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source Electronic Journals Library; MEDLINE; New England Journal of Medicine
subjects Adult
Contrast agents
Contrast Media
Female
Humans
Hysterosalpingography - methods
Infertility
Infertility, Female - diagnostic imaging
Live Birth
Medical imaging
Obstetrics
Oils
Pregnancy
Pregnancy Rate
Reproductive health
Water
Womens health
X-rays
Young Adult
title Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women
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