Does calcemia influence the onset of myringosclerosis after myringotomy with the insertion of ventilation tubes?

Abstract Introduction Myringosclerosis is one of the most frequent late complications of the insertion of ventilation tubes, and its aetiopathogenesis remains unknown. The calcification that occurs in the formation of myringosclerosis plaque raises the hypothesis of the presence of a calcium metabol...

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Veröffentlicht in:Acta otorrinolaringologica espanola 2017-11, Vol.68 (6), p.323-327
Hauptverfasser: Branco, Carla, Paço, João
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Paço, João
description Abstract Introduction Myringosclerosis is one of the most frequent late complications of the insertion of ventilation tubes, and its aetiopathogenesis remains unknown. The calcification that occurs in the formation of myringosclerosis plaque raises the hypothesis of the presence of a calcium metabolism disorder. The objective is to determine whether calcemia contributes to the development of myringoscelerosis after insertion of ventilation tubes. Material and methods A longitudinal, prospective, analytical cohort study was conducted in patients undergoing myringotomy with the insertion of ventilation tubes due to otitis media with effusion. Calcemia was evaluated pre-operatively and in the follow-up the appearance of myringosclerosis and the percentage of the tympanum involved were evaluated. Results The study included 156 patients (297 ears), with calcemia values ranging from 7.6 to 10.2 mg/dl. Myringosclerosis was identified in 35.4% of the operated ears. No relationship was found between the appearance of myringosclerosis and calcemia ( p = .596). It was found, however, that the greater the percentage of the tympanum affected by myringosclerosis, the lower the calcemia values ( p = .014). Conclusion The population studied had calcemia values within the normal range, which allows us to infer that no changes in calcium metabolism are required for the development of myringosclerosis. Moreover, unlike in previous studies, higher calcium levels are not associated with more myringosclerosis. Calcemia did not influence the appearance of myringosclerosis after myringotomy with the insertion of ventilation tubes.
doi_str_mv 10.1016/j.otorri.2017.02.003
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The calcification that occurs in the formation of myringosclerosis plaque raises the hypothesis of the presence of a calcium metabolism disorder. The objective is to determine whether calcemia contributes to the development of myringoscelerosis after insertion of ventilation tubes. Material and methods A longitudinal, prospective, analytical cohort study was conducted in patients undergoing myringotomy with the insertion of ventilation tubes due to otitis media with effusion. Calcemia was evaluated pre-operatively and in the follow-up the appearance of myringosclerosis and the percentage of the tympanum involved were evaluated. Results The study included 156 patients (297 ears), with calcemia values ranging from 7.6 to 10.2 mg/dl. Myringosclerosis was identified in 35.4% of the operated ears. No relationship was found between the appearance of myringosclerosis and calcemia ( p = .596). It was found, however, that the greater the percentage of the tympanum affected by myringosclerosis, the lower the calcemia values ( p = .014). Conclusion The population studied had calcemia values within the normal range, which allows us to infer that no changes in calcium metabolism are required for the development of myringosclerosis. Moreover, unlike in previous studies, higher calcium levels are not associated with more myringosclerosis. Calcemia did not influence the appearance of myringosclerosis after myringotomy with the insertion of ventilation tubes.</description><identifier>ISSN: 0001-6519</identifier><identifier>EISSN: 1988-3013</identifier><identifier>EISSN: 2173-5735</identifier><identifier>DOI: 10.1016/j.otorri.2017.02.003</identifier><identifier>PMID: 28522133</identifier><language>eng</language><publisher>Spain: Elsevier España, S.L.U</publisher><subject>Adenoidectomy ; Adolescent ; Adult ; Calcio ; Calcium ; Calcium - blood ; Child ; Child, Preschool ; Ear, Middle - pathology ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Ear Ventilation ; Miringoesclerosis ; Myringosclerosis ; Myringosclerosis - blood ; Myringosclerosis - epidemiology ; Myringosclerosis - etiology ; Myringosclerosis - pathology ; Otitis Media with Effusion - surgery ; Otolaryngology ; Portugal - epidemiology ; Postoperative Complications - blood ; Postoperative Complications - epidemiology ; Postoperative Complications - etiology ; Postoperative Complications - pathology ; Prospective Studies ; Tonsillectomy ; Tubos de ventilación ; Ventilation tubes ; Young Adult</subject><ispartof>Acta otorrinolaringologica espanola, 2017-11, Vol.68 (6), p.323-327</ispartof><rights>Elsevier España, S.L.U. and Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello</rights><rights>2017 Elsevier España, S.L.U. and Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello</rights><rights>Copyright © 2017 Elsevier España, S.L.U. and Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c332t-16660979fa3ba92063be3ecae88821d10d9feeb552ec21e6b5f4bc12d77fd3633</citedby><cites>FETCH-LOGICAL-c332t-16660979fa3ba92063be3ecae88821d10d9feeb552ec21e6b5f4bc12d77fd3633</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0001651917300857$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28522133$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Branco, Carla</creatorcontrib><creatorcontrib>Paço, João</creatorcontrib><title>Does calcemia influence the onset of myringosclerosis after myringotomy with the insertion of ventilation tubes?</title><title>Acta otorrinolaringologica espanola</title><addtitle>Acta Otorrinolaringol Esp</addtitle><description>Abstract Introduction Myringosclerosis is one of the most frequent late complications of the insertion of ventilation tubes, and its aetiopathogenesis remains unknown. The calcification that occurs in the formation of myringosclerosis plaque raises the hypothesis of the presence of a calcium metabolism disorder. The objective is to determine whether calcemia contributes to the development of myringoscelerosis after insertion of ventilation tubes. Material and methods A longitudinal, prospective, analytical cohort study was conducted in patients undergoing myringotomy with the insertion of ventilation tubes due to otitis media with effusion. Calcemia was evaluated pre-operatively and in the follow-up the appearance of myringosclerosis and the percentage of the tympanum involved were evaluated. Results The study included 156 patients (297 ears), with calcemia values ranging from 7.6 to 10.2 mg/dl. Myringosclerosis was identified in 35.4% of the operated ears. No relationship was found between the appearance of myringosclerosis and calcemia ( p = .596). It was found, however, that the greater the percentage of the tympanum affected by myringosclerosis, the lower the calcemia values ( p = .014). Conclusion The population studied had calcemia values within the normal range, which allows us to infer that no changes in calcium metabolism are required for the development of myringosclerosis. Moreover, unlike in previous studies, higher calcium levels are not associated with more myringosclerosis. Calcemia did not influence the appearance of myringosclerosis after myringotomy with the insertion of ventilation tubes.</description><subject>Adenoidectomy</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Calcio</subject><subject>Calcium</subject><subject>Calcium - blood</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Ear, Middle - pathology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Ear Ventilation</subject><subject>Miringoesclerosis</subject><subject>Myringosclerosis</subject><subject>Myringosclerosis - blood</subject><subject>Myringosclerosis - epidemiology</subject><subject>Myringosclerosis - etiology</subject><subject>Myringosclerosis - pathology</subject><subject>Otitis Media with Effusion - surgery</subject><subject>Otolaryngology</subject><subject>Portugal - epidemiology</subject><subject>Postoperative Complications - blood</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative Complications - etiology</subject><subject>Postoperative Complications - pathology</subject><subject>Prospective Studies</subject><subject>Tonsillectomy</subject><subject>Tubos de ventilación</subject><subject>Ventilation tubes</subject><subject>Young Adult</subject><issn>0001-6519</issn><issn>1988-3013</issn><issn>2173-5735</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFv1DAQhS0EotvCP0AoRy4JM_bGTi4gVKAgVeqh5Ww5zoR6SeLFdor239fpthy4cLLGem9G73uMvUGoEFC-31U--RBcxQFVBbwCEM_YBtumKQWgeM42AIClrLE9Yacx7gDkFpV6yU54U3OOQmzY_rOnWFgzWpqcKdw8jAvNlop0S4WfI6XCD8V0CG7-6aMdKfjoYmGGROHpO_npUPxx6fbB5LIpJOfn1XhHc3KjeRjT0lH8-Iq9GMwY6fXje8Z-fP1yc_6tvLy6-H7-6bK0QvBUopQSWtUORnSm5SBFR4KsoaZpOPYIfTsQdXXNyXIk2dXDtrPIe6WGXkghzti749598L8XiklPLloaRzOTX6LGFqARCtQq3R6lNoeLgQa9D24y4aAR9Mpa7_SRtV5Za-A6s862t48Xlm6i_q_pCW4WfDgKKOe8cxR0tG6F27tANuneu_9d-HeBHd3sclu_6EBx55cwZ4YadcwGfb32vdaNSuRwtRL3SrCphg</recordid><startdate>20171101</startdate><enddate>20171101</enddate><creator>Branco, Carla</creator><creator>Paço, João</creator><general>Elsevier España, S.L.U</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20171101</creationdate><title>Does calcemia influence the onset of myringosclerosis after myringotomy with the insertion of ventilation tubes?</title><author>Branco, Carla ; Paço, João</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c332t-16660979fa3ba92063be3ecae88821d10d9feeb552ec21e6b5f4bc12d77fd3633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adenoidectomy</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Calcio</topic><topic>Calcium</topic><topic>Calcium - blood</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Ear, Middle - pathology</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Ear Ventilation</topic><topic>Miringoesclerosis</topic><topic>Myringosclerosis</topic><topic>Myringosclerosis - blood</topic><topic>Myringosclerosis - epidemiology</topic><topic>Myringosclerosis - etiology</topic><topic>Myringosclerosis - pathology</topic><topic>Otitis Media with Effusion - surgery</topic><topic>Otolaryngology</topic><topic>Portugal - epidemiology</topic><topic>Postoperative Complications - blood</topic><topic>Postoperative Complications - epidemiology</topic><topic>Postoperative Complications - etiology</topic><topic>Postoperative Complications - pathology</topic><topic>Prospective Studies</topic><topic>Tonsillectomy</topic><topic>Tubos de ventilación</topic><topic>Ventilation tubes</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Branco, Carla</creatorcontrib><creatorcontrib>Paço, João</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta otorrinolaringologica espanola</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Branco, Carla</au><au>Paço, João</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Does calcemia influence the onset of myringosclerosis after myringotomy with the insertion of ventilation tubes?</atitle><jtitle>Acta otorrinolaringologica espanola</jtitle><addtitle>Acta Otorrinolaringol Esp</addtitle><date>2017-11-01</date><risdate>2017</risdate><volume>68</volume><issue>6</issue><spage>323</spage><epage>327</epage><pages>323-327</pages><issn>0001-6519</issn><eissn>1988-3013</eissn><eissn>2173-5735</eissn><abstract>Abstract Introduction Myringosclerosis is one of the most frequent late complications of the insertion of ventilation tubes, and its aetiopathogenesis remains unknown. The calcification that occurs in the formation of myringosclerosis plaque raises the hypothesis of the presence of a calcium metabolism disorder. The objective is to determine whether calcemia contributes to the development of myringoscelerosis after insertion of ventilation tubes. Material and methods A longitudinal, prospective, analytical cohort study was conducted in patients undergoing myringotomy with the insertion of ventilation tubes due to otitis media with effusion. Calcemia was evaluated pre-operatively and in the follow-up the appearance of myringosclerosis and the percentage of the tympanum involved were evaluated. Results The study included 156 patients (297 ears), with calcemia values ranging from 7.6 to 10.2 mg/dl. Myringosclerosis was identified in 35.4% of the operated ears. No relationship was found between the appearance of myringosclerosis and calcemia ( p = .596). It was found, however, that the greater the percentage of the tympanum affected by myringosclerosis, the lower the calcemia values ( p = .014). Conclusion The population studied had calcemia values within the normal range, which allows us to infer that no changes in calcium metabolism are required for the development of myringosclerosis. Moreover, unlike in previous studies, higher calcium levels are not associated with more myringosclerosis. Calcemia did not influence the appearance of myringosclerosis after myringotomy with the insertion of ventilation tubes.</abstract><cop>Spain</cop><pub>Elsevier España, S.L.U</pub><pmid>28522133</pmid><doi>10.1016/j.otorri.2017.02.003</doi><tpages>5</tpages></addata></record>
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source MEDLINE; Elsevier ScienceDirect Journals; Alma/SFX Local Collection
subjects Adenoidectomy
Adolescent
Adult
Calcio
Calcium
Calcium - blood
Child
Child, Preschool
Ear, Middle - pathology
Female
Follow-Up Studies
Humans
Male
Middle Ear Ventilation
Miringoesclerosis
Myringosclerosis
Myringosclerosis - blood
Myringosclerosis - epidemiology
Myringosclerosis - etiology
Myringosclerosis - pathology
Otitis Media with Effusion - surgery
Otolaryngology
Portugal - epidemiology
Postoperative Complications - blood
Postoperative Complications - epidemiology
Postoperative Complications - etiology
Postoperative Complications - pathology
Prospective Studies
Tonsillectomy
Tubos de ventilación
Ventilation tubes
Young Adult
title Does calcemia influence the onset of myringosclerosis after myringotomy with the insertion of ventilation tubes?
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