Sphingomyelin synthase 2 deficiency inhibits the induction of murine colitis‐associated colon cancer
ABSTRACT Sphingomyelin synthase 2 (SMS2) is the synthetic enzyme of sphingomyelin (SM), which regulates membrane fluidity and microdomain structure. SMS2 plays a role in LPS‐induced lung injury and inflammation; however, its role in inflammation‐mediated tumorigenesis is unclear. We investigated the...
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Veröffentlicht in: | The FASEB journal 2017-09, Vol.31 (9), p.3816-3830 |
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Sprache: | eng |
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