Sphingomyelin synthase 2 deficiency inhibits the induction of murine colitis‐associated colon cancer

ABSTRACT Sphingomyelin synthase 2 (SMS2) is the synthetic enzyme of sphingomyelin (SM), which regulates membrane fluidity and microdomain structure. SMS2 plays a role in LPS‐induced lung injury and inflammation; however, its role in inflammation‐mediated tumorigenesis is unclear. We investigated the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The FASEB journal 2017-09, Vol.31 (9), p.3816-3830
Hauptverfasser: Ohnishi, Toshio, Hashizume, Chieko, Taniguchi, Makoto, Furumoto, Hidehiro, Han, Jia, Gao, Rongfen, Kinami, Shinichi, Kosaka, Takeo, Okazaki, Toshiro
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!